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冠状动脉的增量网络模拟模型。

Incremental network analogue model of the coronary artery.

作者信息

Wang J Z, Tie B, Welkowitz W, Kostis J, Semmlow J

出版信息

Med Biol Eng Comput. 1989 Jul;27(4):416-22. doi: 10.1007/BF02441434.

DOI:10.1007/BF02441434
PMID:2601469
Abstract

From Newton's equation and the continuity equation, an equivalent analogue circuit model can be derived for each small segment of the coronary arteries. Sapoznikov divided the coronary artery tree into 116 segments. By replacing each segment with its analogue circuit model, a final incremental network model was derived. The model was tested using typical physical parameters under normal conditions, as well as in the presence of coronary artery stenosis. In the case of stenosis, the arteriolar flow with and without autoregulation were compared. The model shows good agreement with the reported effects of stenoses and heart rate on coronary blood flow.

摘要

根据牛顿方程和连续性方程,可以为冠状动脉的每个小片段推导出一个等效的模拟电路模型。萨波兹尼科夫将冠状动脉树划分为116个片段。通过用其模拟电路模型替换每个片段,得出了一个最终的增量网络模型。该模型在正常条件下以及存在冠状动脉狭窄的情况下,使用典型物理参数进行了测试。在狭窄的情况下,比较了有和没有自动调节时的小动脉血流。该模型与所报道的狭窄和心率对冠状动脉血流的影响显示出良好的一致性。

相似文献

1
Incremental network analogue model of the coronary artery.冠状动脉的增量网络模拟模型。
Med Biol Eng Comput. 1989 Jul;27(4):416-22. doi: 10.1007/BF02441434.
2
Transient integral boundary layer method to calculate the translesional pressure drop and the fractional flow reserve in myocardial bridges.用于计算心肌桥跨病变压力阶差和血流储备分数的瞬态积分边界层方法
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Am J Physiol Heart Circ Physiol. 2005 Dec;289(6):H2559-65. doi: 10.1152/ajpheart.00561.2005. Epub 2005 Aug 19.
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Doppler color flow mapping of epicardial coronary arteries: initial observations.心外膜冠状动脉的多普勒彩色血流图:初步观察
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Tree structure and branching characteristics of the right coronary artery in a right-dominant human heart.
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引用本文的文献

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A Numerical Model for Simulating the Hemodynamic Effects of Enhanced External Counterpulsation on Coronary Arteries.一种用于模拟增强型体外反搏对冠状动脉血流动力学影响的数值模型。
Front Physiol. 2021 Apr 12;12:656224. doi: 10.3389/fphys.2021.656224. eCollection 2021.
2
Effects of Mechanical Dyssynchrony on Coronary Flow: Insights From a Computational Model of Coupled Coronary Perfusion With Systemic Circulation.机械不同步对冠状动脉血流的影响:来自冠状动脉灌注与体循环耦合计算模型的见解
Front Physiol. 2020 Aug 14;11:915. doi: 10.3389/fphys.2020.00915. eCollection 2020.
3
A patient-specific lumped-parameter model of coronary circulation.

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