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冠状动脉的增量网络模拟模型。

Incremental network analogue model of the coronary artery.

作者信息

Wang J Z, Tie B, Welkowitz W, Kostis J, Semmlow J

出版信息

Med Biol Eng Comput. 1989 Jul;27(4):416-22. doi: 10.1007/BF02441434.

Abstract

From Newton's equation and the continuity equation, an equivalent analogue circuit model can be derived for each small segment of the coronary arteries. Sapoznikov divided the coronary artery tree into 116 segments. By replacing each segment with its analogue circuit model, a final incremental network model was derived. The model was tested using typical physical parameters under normal conditions, as well as in the presence of coronary artery stenosis. In the case of stenosis, the arteriolar flow with and without autoregulation were compared. The model shows good agreement with the reported effects of stenoses and heart rate on coronary blood flow.

摘要

根据牛顿方程和连续性方程,可以为冠状动脉的每个小片段推导出一个等效的模拟电路模型。萨波兹尼科夫将冠状动脉树划分为116个片段。通过用其模拟电路模型替换每个片段,得出了一个最终的增量网络模型。该模型在正常条件下以及存在冠状动脉狭窄的情况下,使用典型物理参数进行了测试。在狭窄的情况下,比较了有和没有自动调节时的小动脉血流。该模型与所报道的狭窄和心率对冠状动脉血流的影响显示出良好的一致性。

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