Pierluisi G J, Terndrup T E
Department of Critical Care, SUNY Health Sciences Center 13210.
Pediatr Emerg Care. 1989 Dec;5(4):211-5. doi: 10.1097/00006565-198912000-00002.
Local anesthetic infiltration of wounds causes pain which distresses children. A painless topical anesthetic solution containing tetracaine, adrenaline, and cocaine (TAC) may reduce this distress. We hypothesized that the use of TAC for anesthesia may reduce the utilization of sedation for laceration repair. We performed a retrospective review of all pediatric emergency department (PED) patients receiving parenteral meperidine, promethazine, and chlorpromazine (DPT) during the period after TAC became routinely available. For comparison, data from a recent retrospective study of DPT (preTAC) use in the same PED were used. There was a reduction in the percent of total PED patients receiving DPT, from 1.7% preTAC to 1.2% during the TAC period (P less than 0.05). During the TAC period, there were no significant changes in patient volume or case-mix indicators. Of the major indications for DPT, there was no significant change in the percent receiving DPT for fractures, abscesses, burns, foreign body removal, or head injuries. However, there was a significant reduction in the percent of patients with lacerations receiving DPT during the experimental period, from 12% to 7.6% (P less than 0.05). There were no significant differences in laceration frequency (119/mo and 116/mo), length (2.7 and 2.7 cm), location (85% and 93% total for face and digits), or complexity (64% and 63%) for preTAC and TAC periods, respectively. We conclude that TAC used for local anesthesia may reduce the need for sedation in PED patients with lacerations that require suturing.
伤口局部麻醉浸润会引起疼痛,令儿童痛苦。一种含有丁卡因、肾上腺素和可卡因(TAC)的无痛局部麻醉溶液可能会减轻这种痛苦。我们推测,使用TAC进行麻醉可能会减少用于撕裂伤修复的镇静剂的使用。我们对TAC常规可用后期间所有接受胃肠外哌替啶、异丙嗪和氯丙嗪(DPT)的儿科急诊科(PED)患者进行了回顾性研究。为了进行比较,使用了来自同一PED最近一项关于DPT(TAC之前)使用的回顾性研究的数据。接受DPT的PED患者总数百分比有所下降,从TAC之前的1.7%降至TAC期间的1.2%(P小于0.05)。在TAC期间,患者数量或病例组合指标没有显著变化。在DPT的主要适应症中,因骨折、脓肿、烧伤、异物取出或头部受伤接受DPT的百分比没有显著变化。然而,在实验期间,撕裂伤患者接受DPT的百分比显著下降,从12%降至7.6%(P小于0.05)。TAC之前和TAC期间的撕裂伤频率(分别为每月119例和116例)、长度(分别为2.7厘米和2.7厘米)、位置(面部和手指总计分别为85%和93%)或复杂程度(分别为64%和63%)没有显著差异。我们得出结论,用于局部麻醉的TAC可能会减少需要缝合的PED撕裂伤患者对镇静的需求。