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输尿管乙状结肠吻合术所致高氨血症性昏迷

Hyperammonaemic coma in ureterosigmoid urinary diversion.

作者信息

Oliver R M, Talbot S, Raman G V

机构信息

Department of Renal Medicine, University of Southampton, St Mary's Hospital, Portsmouth, UK.

出版信息

Postgrad Med J. 1989 Jul;65(765):502-4. doi: 10.1136/pgmj.65.765.502.

DOI:10.1136/pgmj.65.765.502
PMID:2602245
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2429441/
Abstract

We report on a patient with ureterosigmoid anastomosis, who presented with recurrent episodes of confusion, agitation and aggressive behaviour, culminating in coma. Investigations revealed profound hyperammonaemia, which responded to treatment with sodium benzoate and sodium phenylacetate. No definite cause was found for the abnormality, apart from possible urinary tract infection. The patient remains well on a protein restricted diet with mildly elevated levels of plasma ammonia.

摘要

我们报告了一例输尿管乙状结肠吻合术患者,该患者反复出现意识模糊、烦躁和攻击行为,最终陷入昏迷。检查发现严重高氨血症,经苯甲酸钠和苯乙酸钠治疗后有所缓解。除了可能的尿路感染外,未发现该异常的确切病因。该患者在蛋白质限制饮食下情况良好,血浆氨水平轻度升高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd8/2429441/b2d9435f7deb/postmedj00175-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd8/2429441/b2d9435f7deb/postmedj00175-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffd8/2429441/b2d9435f7deb/postmedj00175-0070-a.jpg

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1
Hyperammonaemic coma in ureterosigmoid urinary diversion.输尿管乙状结肠吻合术所致高氨血症性昏迷
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Hyperammonemia in Urinary Tract Infections.尿路感染中的高氨血症

本文引用的文献

1
Ammonia intoxication following ureterosigmoidostomy in a patient with liver disease.
Lancet. 1958 Nov 1;2(7053):937-9. doi: 10.1016/s0140-6736(58)90429-x.
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Diversion of urine to the intestines as a factor in ammoniagenic coma.
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Hyperammonemic encephalopathy caused by infection in a neurogenic bladder.神经源性膀胱感染所致高氨血症性脑病
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PLoS One. 2015 Aug 20;10(8):e0136220. doi: 10.1371/journal.pone.0136220. eCollection 2015.
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Ammonia-induced coma after ureterosigmoidostomy.输尿管乙状结肠吻合术后氨性昏迷
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Lancet. 1985 Dec 7;2(8467):1271-4. doi: 10.1016/s0140-6736(85)91554-5.
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New pathways of nitrogen excretion in inborn errors of urea synthesis.
Lancet. 1979 Sep 1;2(8140):452-4. doi: 10.1016/s0140-6736(79)91503-4.