Morikawa Mako, Okada Takashi, Ando Masahiko, Aleksic Branko, Kunimoto Shohko, Nakamura Yukako, Kubota Chika, Uno Yota, Tamaji Ai, Hayakawa Norika, Furumura Kaori, Shiino Tomoko, Morita Tokiko, Ishikawa Naoko, Ohoka Harue, Usui Hinako, Banno Naomi, Murase Satomi, Goto Setsuko, Kanai Atsuko, Masuda Tomoko, Ozaki Norio
Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan.
Sci Rep. 2015 May 29;5:10520. doi: 10.1038/srep10520.
Although the association between social support and postpartum depression has been previously investigated, its causal relationship remains unclear. Therefore, we examined prospectively whether social support during pregnancy affected postpartum depression. Social support and depressive symptoms were assessed by Japanese version of Social Support Questionnaire (J-SSQ) and Edinburgh Postnatal Depression Scale (EPDS), among 877 pregnant women in early pregnancy and at one month postpartum. First, J-SSQ was standardized among peripartum women. The J-SSQ was found to have a two-factor structure, with Number and Satisfaction subscales, by exploratory and confirmatory factor analyses. Analysis of covariance was performed to examine how EPDS and J-SSQ scores during pregnancy affected the EPDS score at postpartum. Significant associations were found between postpartum EPDS score and both EPDS and total scores on the Number subscales during pregnancy (β = 0.488 and -0.054, ps < 0.001). Specifically, this negative correlation was stronger in depressive than non-depressive groups. Meanwhile, total score on Satisfaction subscales was not significantly associated with postpartum EPDS score. These results suggest that having a larger number of supportive persons during pregnancy helps protect against postpartum depression, and that this effect is greater in depressive than non-depressive pregnant women. This finding is expected to be vitally important in preventive interventions.
尽管先前已经对社会支持与产后抑郁之间的关联进行了研究，但其因果关系仍不明确。因此，我们前瞻性地研究了孕期的社会支持是否会影响产后抑郁。我们使用日本版社会支持问卷（J - SSQ）和爱丁堡产后抑郁量表（EPDS）对877名孕早期及产后1个月的孕妇进行了社会支持和抑郁症状评估。首先，对围产期女性的J - SSQ进行了标准化。通过探索性和验证性因素分析发现，J - SSQ具有双因素结构，包括数量和满意度分量表。进行协方差分析以研究孕期的EPDS和J - SSQ得分如何影响产后的EPDS得分。发现产后EPDS得分与孕期EPDS得分及数量分量表的总分均存在显著关联（β = 0.488和 - 0.054，p < 0.001）。具体而言，这种负相关在抑郁组比非抑郁组更强。同时，满意度分量表的总分与产后EPDS得分无显著关联。这些结果表明，孕期有更多支持性的人有助于预防产后抑郁，并且这种影响在抑郁孕妇中比非抑郁孕妇更大。这一发现预计在预防性干预中至关重要。
