纳米系统:纳米合金、金属、双金属和磁性纳米颗粒在生物医学应用中的使用。
Nanosystems: the use of nanoalloys, metallic, bimetallic, and magnetic nanoparticles in biomedical applications.
作者信息
McNamara Karrina, Tofail Syed A M
机构信息
Department of Physics & Energy, and Materials and Surface Science Institute, University of Limerick, Limerick, Ireland.
出版信息
Phys Chem Chem Phys. 2015 Nov 14;17(42):27981-95. doi: 10.1039/c5cp00831j. Epub 2015 May 29.
There is a growing interest in the use of nanosystems such as nanoalloys, bimetallic nanoparticles, metallic nanoparticles and magnetic nanoparticles in biomedical applications. These applications can be as diverse as hyperthermic treatments; targeted drug delivery; bio-imaging; cell labelling and gene delivery. The use of nanoalloys in these applications has received only limited attention due to the fact that there were many unanswered questions and concerns regarding nanoparticles and nanoalloys such as their stability over time, tendency to agglomerate, chemical activity, ease of oxidation, biocompatibility and cytotoxicity. In this chapter we survey current applications and advances in magnetic nanoparticles used in these biomedical applications so as to understand the materials properties that can pave the way for the use of nanoalloys as a potential alternative or improve solutions that are offered by current materials.
人们对纳米系统(如纳米合金、双金属纳米颗粒、金属纳米颗粒和磁性纳米颗粒)在生物医学应用中的使用兴趣与日俱增。这些应用范围广泛,包括热疗、靶向药物递送、生物成像、细胞标记和基因递送。由于关于纳米颗粒和纳米合金存在许多未解决的问题和担忧,例如它们随时间的稳定性、团聚倾向、化学活性、氧化易感性、生物相容性和细胞毒性,纳米合金在这些应用中的使用仅受到了有限的关注。在本章中,我们将概述磁性纳米颗粒在这些生物医学应用中的当前应用和进展,以便了解那些可为纳米合金作为潜在替代品的使用铺平道路或改进现有材料所提供解决方案的材料特性。