van der Ploeg Hidde P, Møller Simone Visbjerg, Hannerz Harald, van der Beek Allard J, Holtermann Andreas
Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center Amsterdam, van der Boechorststraat 7, NL-1081 BT, Amsterdam, The Netherlands.
National Research Centre for the Working Environment, Amsterdam, Denmark.
Int J Behav Nutr Phys Act. 2015 Jun 2;12:71. doi: 10.1186/s12966-015-0233-1.
Prolonged sitting has been negatively associated with a range of non-communicably diseases. However, the role of occupational sitting is less clear, and little is known on the changes of occupational sitting in a working population over time. The present study aimed to determine 1) temporal changes in occupational sitting time between 1990 and 2010 in the Danish workforce; 2) the association and possible dose-response relationship between occupational sitting time and all-cause mortality.
This study analysed data from the Danish Work Environment Cohort Study (DWECS), which is a cohort study of the Danish working population conducted in five yearly intervals between 1990 and 2010. Occupational sitting time is self-reported in the DWECS. To determine the association with all-cause mortality, the DWECS was linked to the Danish Register of Causes of Death via the Central Person Register.
Between 1990 and 2010 the proportion of the Danish workforce who sat for at least three quarters of their work time gradually increased from 33.1 to 39.1%. All-cause mortality analyses were performed with 149,773 person-years of observation and an average follow-up of 12.61 years, during which 533 deaths were registered. None of the presented analyses found a statistically significant association between occupational sitting time and all-cause mortality. The hazard ratio for all-cause mortality was 0.97 (95% CI: 0.79; 1.18) when ≥24 hr/wk occupational sitting time was compared to <24 hr/wk for the 1990-2005 waves.
Occupational sitting time increased by 18% in the Danish workforce, which seemed to be limited to people with high socio-economic status. If this increase is accompanied by increases in total sitting time, this development has serious public health implications, given the detrimental associations between total sitting time and mortality. The current study was inconclusive on the specific role that occupational sitting might play in the increased all-cause mortality risk associated with the total volume of sitting.
长时间坐着与一系列非传染性疾病存在负相关。然而,职业性久坐的作用尚不清楚,对于工作人群中职业性久坐随时间的变化也知之甚少。本研究旨在确定:1)1990年至2010年丹麦劳动力中职业性久坐时间的时间变化;2)职业性久坐时间与全因死亡率之间的关联及可能的剂量反应关系。
本研究分析了丹麦工作环境队列研究(DWECS)的数据,该研究是对丹麦工作人群进行的队列研究,在1990年至2010年期间每五年进行一次。职业性久坐时间由DWECS中的自我报告得出。为了确定与全因死亡率的关联,DWECS通过中央人口登记处与丹麦死亡原因登记处相链接。
1990年至2010年期间,丹麦劳动力中工作时间至少四分之三都坐着的比例从33.1%逐渐增加到39.1%。全因死亡率分析共进行了149,773人年的观察,平均随访12.61年,在此期间登记了533例死亡。所有呈现的分析均未发现职业性久坐时间与全因死亡率之间存在统计学上的显著关联。在1990 - 2005年各波次中,当每周职业性久坐时间≥24小时与<24小时相比较时,全因死亡率的风险比为0.97(95%置信区间:0.79;1.18)。
丹麦劳动力的职业性久坐时间增加了18%,这似乎仅限于社会经济地位较高的人群。如果这种增加伴随着总久坐时间的增加,鉴于总久坐时间与死亡率之间的有害关联,这一发展对公众健康具有严重影响。目前的研究对于职业性久坐可能在与总久坐量相关的全因死亡率增加中所起的具体作用尚无定论。