Angeles-Han Sheila T, Yeh Steven, McCracken Courtney, Jenkins Kirsten, Stryker Daneka, Myoung Erica, Vogler Larry B, Rouster-Stevens Kelly, Lambert Scott R, Harrison Melanie J, Prahalad Sampath, Drews-Botsch Carolyn
Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
Emory University School of Medicine, Atlanta, Georgia.
Arthritis Care Res (Hoboken). 2015 Nov;67(11):1513-20. doi: 10.1002/acr.22627.
The Effects of Youngsters' Eyesight on Quality of Life (EYE-Q) is a novel measure of vision-related quality of life (QOL) and function in children. We aim to determine the validity of the EYE-Q in childhood uveitis.
We abstracted medical record data on arthritis and uveitis in a convenience sample of children with juvenile idiopathic arthritis (JIA) and/or uveitis. In addition to the EYE-Q, parents and patients completed questionnaires on overall QOL (Pediatric Quality of Life Inventory [PedsQL]), and physical functioning (Childhood Health Assessment Questionnaire [C-HAQ]).
Among 57 children (8 JIA, 24 JIA and uveitis, 25 uveitis alone), 102 ocular examinations were performed within 1 month of completing questionnaires. Uveitis patients had bilateral disease (69%), anterior involvement (78%), synechiae (51%), and cataracts (49%). Children with vision loss in their better eye (visual acuity [VA] 20/50 or worse) had worse EYE-Q (P = 0.006) and PedsQL (P = 0.028) scores, but not C-HAQ scores. The EYE-Q moderately correlated with logMAR VA (rs = -0.43), PedsQL (rs = 0.43), and C-HAQ (rs = -0.45), but was not correlated with anterior chamber cells or intraocular pressure. The PedsQL and C-HAQ did not correlate with VA or cells. There were strong correlations between the parent and child EYE-Q (rs = 0.62). Cronbach's α for the child report was 0.91. The EYE-Q had strong test-retest reliability (rs = 0.75).
The EYE-Q may be an important tool in the assessment of visual outcomes in childhood uveitis and an improvement over general measures in detecting changes in vision-related function.
青少年视力对生活质量的影响（EYE-Q）是一种衡量儿童视力相关生活质量（QOL）和功能的新方法。我们旨在确定EYE-Q在儿童葡萄膜炎中的有效性。
我们从患有青少年特发性关节炎（JIA）和/或葡萄膜炎的儿童便利样本中提取了有关关节炎和葡萄膜炎的病历数据。除了EYE-Q之外，父母和患者还完成了关于总体生活质量（儿童生活质量量表[PedsQL]）和身体功能（儿童健康评估问卷[C-HAQ]）的问卷调查。
在57名儿童（8名单纯JIA，24名JIA合并葡萄膜炎，25名单纯葡萄膜炎）中，在完成问卷调查后的1个月内进行了102次眼科检查。葡萄膜炎患者患有双侧疾病（69%）、前部受累（78%）、粘连（51%）和白内障（49%）。最佳眼视力丧失（视力[VA]为20/50或更差）的儿童的EYE-Q得分（P = 0.006）和PedsQL得分（P = 0.028）更差，但C-HAQ得分无差异。EYE-Q与logMAR VA（rs = -0.43）、PedsQL（rs = 0.43）和C-HAQ（rs = -0.45）中度相关，但与前房细胞或眼压无关。PedsQL和C-HAQ与VA或细胞无关。父母和儿童的EYE-Q之间存在强相关性（rs = 0.62）。儿童报告的Cronbach's α为0.91。EYE-Q具有很强的重测信度（rs = 0.75）。
EYE-Q可能是评估儿童葡萄膜炎视觉预后的重要工具，并且在检测视力相关功能变化方面比一般测量方法有所改进。
