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食用富含黄油的饮食及其替换为富含特级初榨橄榄油的饮食对绝经后女性人体测量学、代谢和血脂状况的影响。

Impact of the consumption of a rich diet in butter and it replacement for a rich diet in extra virgin olive oil on anthropometric, metabolic and lipid profile in postmenopausal women.

作者信息

Anderson-Vasquez Hazel Ester, Pérez-Martínez Pablo, Ortega Fernández Pablo, Wanden-Berghe Carmina

机构信息

Universidad del Zulia, Laboratorio de Investigación y Desarrollo en Nutrición. Universidad de Córdoba, Doctorado en Nutrición y Metabolismo..

Universidad de Córdoba, Doctorado en Nutrición y Metabolismo. Unidad de Lípidos y Ateroesclerosis. IMIBIC/Hospital Universitario Reina Sofia, Universidad de Córdoba, and CIBER Fisiopatologia Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, España..

出版信息

Nutr Hosp. 2015 Jun 1;31(6):2561-70. doi: 10.3305/nh.2015.31.6.8732.

DOI:10.3305/nh.2015.31.6.8732
PMID:26040366
Abstract

OBJECTIVE

To analyze the impact of the substitution of a rich diet in saturated fats with a rich diet in monounsaturated fats on anthropometric, metabolic and lipid profile in postmenopausal women.

MATERIAL AND METHODS

A prospective, longitudinal and comparative study where 18 postmenopausal women participated in two periods of dietary intervention of 28 days each one: 1) (SAT diet) consumed butter. Caloric formula (CF) = 15% protein, 38% fat. [20% saturated fat (SFA), 12% monounsaturated fat (MUFA) and 47% carbohydrates and 6% polyunsaturated (PUFA)]. b) Period MONO: with extra virgin olive oil (EVOO). CF = 15% protein, 38% fat (<10% SFA, 22% PUFA and 6% MUFA) and 47% carbohydrates. Size and body composition, glucose, insulin, HOMA, TC, HDL-C, LDL-C, VLDL-C, TG, TC/HDL-C, LDL-C/HDL-C, TG/HDL-C and non-HDL-C/HDL.C were measured; dietary Anamnesis/24 hours, daily food record. ANOVA and Bonferroni statistical analysis (SPSS 20) was applied.

RESULTS

The age was 56 ± 5 years, BMI 29.8 ± 3.1 kg/m2, waist circumference: 93.2 ± 10.1 cm, waist/hip ratio: 0.86 ± 0.14, waist/height: 0.59 ± 0.06 and 38.6 ± 4% body fat (NS). Lipid profile: SAT diet increased TC (p <0.001), LDL-C (p <0.002) and non HDL-Cholesterol (p <0.000), HDL-C increased in MONO diet (p <0.000). SAT diet: TC/HDL-c ratio, Non col HDL-c/HDL-c, LDL-c/HDL-c (p <0.000) and TG/HDL-c (p <0.000). In MONO diet decreased TC/HDL-c (p <0.015) and TG/HDL-c (p <0.016).

CONCLUSIONS

The SAT diet increased cardiovascular risk, while the MONO diet decreased the risk to develop the metabolic syndrome components and choronary heart disease.

摘要

目的

分析用富含单不饱和脂肪的饮食替代富含饱和脂肪的饮食对绝经后女性人体测量学、代谢和血脂谱的影响。

材料与方法

一项前瞻性、纵向和对照研究,18名绝经后女性参与了两个为期28天的饮食干预阶段:1)(饱和脂肪饮食)食用黄油。热量配方(CF)=15%蛋白质,38%脂肪。[20%饱和脂肪(SFA),12%单不饱和脂肪(MUFA),47%碳水化合物和6%多不饱和脂肪(PUFA)]。b) 单不饱和脂肪饮食阶段:食用特级初榨橄榄油(EVOO)。CF = 15%蛋白质,38%脂肪(<10% SFA,22% PUFA和6% MUFA)和47%碳水化合物。测量身高、身体成分、血糖、胰岛素、HOMA、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、极低密度脂蛋白胆固醇(VLDL-C)、甘油三酯(TG)、TC/HDL-C、LDL-C/HDL-C、TG/HDL-C和非HDL-C/HDL-C;进行24小时饮食问诊、每日饮食记录。应用方差分析和Bonferroni统计分析(SPSS 20)。

结果

年龄为56±5岁,体重指数(BMI)为29.8±3.1kg/m²,腰围:93.2±10.1cm,腰臀比:0.86±0.14,腰高比:0.59±0.06,体脂率为38.6±4%(无显著性差异)。血脂谱:饱和脂肪饮食使总胆固醇(p<0.001)、低密度脂蛋白胆固醇(p<0.002)和非高密度脂蛋白胆固醇(p<0.000)升高,单不饱和脂肪饮食使高密度脂蛋白胆固醇升高(p<0.000)。饱和脂肪饮食:TC/HDL-c比值、非HDL-c/HDL-c、LDL-c/HDL-c(p<0.000)和TG/HDL-c(p<0.000)。单不饱和脂肪饮食中TC/HDL-c(p<0.015)和TG/HDL-c(p<0.016)降低。

结论

饱和脂肪饮食增加心血管疾病风险,而单不饱和脂肪饮食降低发生代谢综合征组分和冠心病的风险。

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