Cardoso Diuli A, Moreira Annie S B, de Oliveira Glaucia M M, Raggio Luiz Ronir, Rosa Glorimar
Postgraduate Program in Cardiology at the School of Medicine, Universidade Federal do Rio de Janeiro (UFRJ)..
Applied Nutrition Department of Universidade do Estado do Rio de Janeiro (UERJ); Research dietitian and professor at Instituto Nacional de Cardiologia (INC)..
Nutr Hosp. 2015 Nov 1;32(5):2144-52. doi: 10.3305/nh.2015.32.5.9642.
saturated fat restriction has been recommended for coronary arterial disease, but the role of coconut oil (Cocos nucifera L.) extra virgin, lauric acid source in the management of lipid profile remains unclear.
to evaluate the effect of nutritional treatment associated with the consumption of extra virgin coconut oil in anthropometric parameters and lipid profile.
we conducted a longitudinal study of 116 adults of both sexes presenting CAD. Patients were followed in two stages: the first stage (basal-3 months), intensive nutritional treatment. In the second stage (3-6 months), the subjects were divided into two groups: diet group associated with extra virgin coconut oil consumption (GDOC) and diet group (DG). Held monthly anthropometric measurements: body mass, waist circumference (WC), neck circumference (PP), body mass index (BMI). Gauged to collected blood pressure and blood samples were fasted for 12 hours, for total cholesterol analysis and fractions apoproteins (Apo A-1 and B), glucose, glycated hemoglobin (HbA1C), insulin (I). Comparing the averages at the beginning and end of the study employing the paired Student t-independent. And set the diastolic blood pressure by BMI using ANOVA. Analyses were performed using the SPSS statistical package, being significant p < 0.05.
the mean age of the population was 62.4 ± 7.7 years, 63.2% male, 70% elderly, 77.6% infarcted, 52.6% with angina, hypertension and dyslipidemia 100%. In the first stage the nutritional treatment reduced body weight, WC, BMI and PP and insulin concentrations, HbA1C, HOMA-IR and QUICK, without changing the other parameters. In the second stage of the study, it was observed that the GDOC maintained the reduction of body mass, BMI, WC, with a significant difference between groups for DC (-2.1 ± 2,7 cm; p < 0.01). In addition, there was an increase in HDL-C concentrations, Apo A, with significant difference in GD, only for HDL-C (3.1 ± 7.4 mg/dL; p = 0.02).
it was observed that the nutritional treatment associated with extra virgin coconut oil consumption reduced the CC and increased HDL-C levels in patients with CAD.
已建议对冠状动脉疾病患者限制饱和脂肪摄入，但初榨椰子油（椰子属）这种月桂酸来源在脂质谱管理中的作用仍不明确。
评估与食用初榨椰子油相关的营养治疗对人体测量参数和脂质谱的影响。
我们对116名患有冠心病的成年男女进行了一项纵向研究。患者分两个阶段进行随访：第一阶段（基础期 - 3个月），进行强化营养治疗。在第二阶段（3 - 6个月），将受试者分为两组：食用初榨椰子油的饮食组（GDOC）和饮食组（DG）。每月进行人体测量：体重、腰围（WC）、颈围（PP）、体重指数（BMI）。测量血压并采集空腹12小时的血样，用于总胆固醇分析以及载脂蛋白（Apo A - 1和B）、葡萄糖、糖化血红蛋白（HbA1C）、胰岛素（I）的检测。采用配对学生t检验独立样本比较研究开始和结束时的平均值。并使用方差分析按BMI设定舒张压。使用SPSS统计软件包进行分析，p < 0.05具有统计学意义。
研究人群的平均年龄为62.4 ± 7.7岁，男性占63.2%，老年人占70%，心肌梗死患者占77.6%，心绞痛患者占52.6%，高血压和血脂异常患者占100%。在第一阶段，营养治疗降低了体重、WC、BMI和PP以及胰岛素浓度、HbA1C、HOMA - IR和QUICK，而其他参数未改变。在研究的第二阶段，观察到GDOC组维持了体重、BMI、WC的降低，两组间DC存在显著差异（-2.1 ± 2.7 cm；p < 0.01）。此外，HDL - C浓度、Apo A有所增加，GDOC组仅HDL - C有显著差异（3.1 ± 7.4 mg/dL；p = 0.02）。
观察到与食用初榨椰子油相关的营养治疗降低了冠心病患者的CC并提高了HDL - C水平。
