Vannucci A, Nelson E E, Bongiorno D M, Pine D S, Yanovski J A, Tanofsky-Kraff M
Department of Medical and Clinical Psychology,Uniformed Services University of the Health Sciences,Bethesda,MD,USA.
Section on Development and Affective Neuroscience of the National Institute of Mental Health,National Institutes of Health (NIH),DHHS,Bethesda,MD,USA.
Psychol Med. 2015 Oct;45(14):2921-36. doi: 10.1017/S003329171500104X. Epub 2015 Jun 4.
Pediatric loss-of-control (LOC) eating is a robust behavioral precursor to binge-type eating disorders. Elucidating precursors to LOC eating and binge-type eating disorders may refine developmental risk models of eating disorders and inform interventions.
We review evidence within constructs of the Negative Valence Systems (NVS) domain, as specified by the Research Domain Criteria framework. Based on published studies, we propose an integrated NVS model of binge-type eating-disorder risk.
Data implicate altered corticolimbic functioning, neuroendocrine dysregulation, and self-reported negative affect as possible risk factors. However, neuroimaging and physiological data in children and adolescents are sparse, and most prospective studies are limited to self-report measures.
We discuss a broad NVS framework for conceptualizing early risk for binge-type eating disorders. Future neural and behavioral research on the developmental trajectory of LOC and binge-type eating disorders is required.
儿童失控性进食是暴饮暴食型饮食失调的一种强烈行为先兆。阐明失控性进食和暴饮暴食型饮食失调的先兆可能会完善饮食失调的发展风险模型并为干预措施提供依据。
我们根据研究领域标准框架所规定的负性价系统（NVS）领域的结构来回顾证据。基于已发表的研究，我们提出了一个暴饮暴食型饮食失调风险的综合NVS模型。
数据表明皮质边缘功能改变、神经内分泌失调和自我报告的负面情绪可能是风险因素。然而，儿童和青少年的神经影像学和生理学数据稀少，并且大多数前瞻性研究仅限于自我报告测量。
我们讨论了一个用于概念化暴饮暴食型饮食失调早期风险的广泛NVS框架。未来需要对失控性进食和暴饮暴食型饮食失调的发展轨迹进行神经和行为研究。
