游离氯对沙鼠培养的蓝氏贾第鞭毛虫囊肿的灭活作用。
Inactivation of gerbil-cultured Giardia lamblia cysts by free chlorine.
作者信息
Rubin A J, Evers D P, Eyman C M, Jarroll E L
机构信息
Water Resources Center, Ohio State University, Columbus 43210.
出版信息
Appl Environ Microbiol. 1989 Oct;55(10):2592-4. doi: 10.1128/aem.55.10.2592-2594.1989.
Giardia lamblia cysts were harvested from Mongolian gerbils and exposed to free chlorine in buffered water at pH 5, 7, and 9 at 15 degrees C. The contact times required to obtain a 2-log reduction in cyst survival (i.e., a 99% kill) were interpolated from survival curves generated at fixed concentrations of chlorine in the range of 0.25 to about 16 mg/liter. Concentration-time (C.t') products for 99% inactivation ranged from about 120 to nearly 1,500 mg.min/liter. These values are higher than those reported previously for free chlorine using G. lamblia cysts from infected humans. The cysts isolated from gerbils, as with other Giardia cysts, were unusually sensitive to chlorine in alkaline solutions.
从蒙古沙鼠体内采集兰氏贾第鞭毛虫囊肿，并将其置于15摄氏度、pH值分别为5、7和9的缓冲水中，使其接触游离氯。根据在0.25至约16毫克/升的固定氯浓度下生成的存活曲线，推算出囊肿存活率降低2个对数（即99%杀灭率）所需的接触时间。99%灭活的浓度-时间（C.t'）乘积范围约为120至近1500毫克·分钟/升。这些数值高于先前使用来自受感染人类的兰氏贾第鞭毛虫囊肿所报告的游离氯数值。与其他贾第鞭毛虫囊肿一样，从沙鼠体内分离出的囊肿在碱性溶液中对氯异常敏感。
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