Hoff J C, Rice E W, Schaefer F W
Appl Environ Microbiol. 1985 Oct;50(4):1115-7. doi: 10.1128/aem.50.4.1115-1117.1985.
In this study, in vitro excystation and mouse infectivity were compared as methods for quantitatively determining the viability of Giardia muris cysts before and after exposure to free residual chlorine. The mouse infectivity results show that very few cysts (1 to 15) constitute an infectious dose. The results of the inactivation studies indicate that in vitro excystation is an adequate indication of G. muris cyst infectivity for the host and can be used to determine the effects of disinfectants on cyst viability.
在本研究中,对体外脱囊和小鼠感染性这两种方法进行了比较,以定量测定暴露于游离余氯前后微小贾第虫包囊的活力。小鼠感染性结果表明,极少的包囊(1至15个)即构成感染剂量。灭活研究结果表明,体外脱囊是微小贾第虫包囊对宿主感染性的充分指标,可用于确定消毒剂对包囊活力的影响。