Valmaggia Lucia R, Byrne Majella, Day Fern, Broome Matthew R, Johns Louise, Howes Oliver, Power Paddy, Badger Steven, Fusar-Poli Paolo, McGuire Philip K
King's College London, Institute of Psychiatry, United Kingdom.
Outreach and Support in South London, South London and Maudsley NHS Foundation Trust, United Kingdom.
Br J Psychiatry. 2015 Aug;207(2):130-134. doi: 10.1192/bjp.bp.114.150623. Epub 2015 Jun 4.
It is unknown whether prodromal services improve outcomes in those who go on to develop psychosis, and whether these patients are demographically different from the overall first-episode population.
To compare sociodemographic features, duration of untreated psychosis, hospital admission and frequency of compulsory treatment in the first year after the onset of psychosis in patients who present to prodromal services with patients who did not present to services until the first episode of psychosis.
We compared two groups of patients with first-episode psychosis: one who made transition after presenting in the prodromal phase and the other who had presented with a first episode.
The patients who had presented before the first episode were more likely to be employed and less likely to belong to an ethnic minority group. They had a shorter duration of untreated psychosis, and were less likely to have been admitted to hospital and to have required compulsory treatment.
Patients who develop psychosis after being engaged in the prodromal phase have a better short-term clinical outcome than patients who do not present until the first episode. Patients who present during first episodes may be more likely to have sociodemographic features associated with relatively poor outcomes.
前驱期服务是否能改善那些最终发展为精神病患者的预后，以及这些患者在人口统计学特征上是否与首次发作的总体人群不同，目前尚不清楚。
比较前来接受前驱期服务的患者与直到精神病首次发作才前来就诊的患者在精神病发作后第一年的社会人口学特征、未治疗精神病的持续时间、住院情况及强制治疗频率。
我们比较了两组首次发作精神病的患者：一组是在前驱期就诊后病情转变的患者，另一组是首次发作时前来就诊的患者。
首次发作前前来就诊的患者更有可能就业，且较少属于少数民族群体。他们未治疗精神病的持续时间较短，住院及需要强制治疗的可能性较小。
在前驱期就参与治疗的精神病患者比直到首次发作才就诊的患者有更好的短期临床预后。首次发作时前来就诊的患者可能更有可能具有与相对较差预后相关的社会人口学特征。
