1H-苯并三唑羧酸的体内外代谢
Metabolism of 1H-benzotriazolecarboxylic acids in vitro and in vivo.
作者信息
Hoffmann H, Jacobi S
出版信息
Arch Pharm (Weinheim). 1989 Aug;322(8):457-9. doi: 10.1002/ardp.19893220802.
PMID:2604537
Abstract
The 1H-benzotriazolecarboxylic acids 1 and 2 were stable towards oxidative metabolism as well in vitro as in vivo. In the in vivo studies 2.25% of the ester glucuronide of 1H-benzotriazole-5-carboxylic acid was found in urine.
摘要
1H-苯并三唑羧酸1和2在体外和体内对氧化代谢均稳定。在体内研究中，在尿液中发现了1H-苯并三唑-5-羧酸酯葡糖醛酸的2.25%。
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