Garrido Marlucia da Silva, Bührer-Sékula Samira, Souza Alexandra Brito de, Ramasawmy Rajendranath, Quincó Patrícia de Lima, Monte Rossicleia Lins, Santos Lucilaide Oliveira, Perez-Porcuna Tomás Maria, Martinez-Espínosa Flor Ernestina, Saraceni Valéria, Cordeiro-Santos Marcelo
Departamento de Ensino e Pós-Graduação, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brazil.
Programa de Pós-Graduação em Medicina Tropical, Universidade do Estado do Amazonas, Manaus, AM, Brazil.
Rev Soc Bras Med Trop. 2015;48 Suppl 1:63-9. doi: 10.1590/0037-8682-0055-2014. Epub 2015 Mar 1.
Tuberculosis (TB) is one of the infectious diseases that contributes most to the morbidity and mortality of millions of people worldwide. Brazil is one of 22 countries that accounts for 80% of the tuberculosis global burden. The highest incidence rates in Brazil occur in the States of Amazonas and Rio de Janeiro. The aim of this study was to describe the temporal distribution of TB in the State of Amazonas. Between 2001 and 2011, 28,198 cases of tuberculosis were reported in Amazonas, distributed among 62 municipalities, with the capital Manaus reporting the highest (68.7%) concentration of cases. Tuberculosis was more prevalent among males (59.3%) aged 15 to 34 years old (45.5%), whose race/color was predominantly pardo (64.7%) and who had pulmonary TB (84.3%). During this period, 81 cases of multidrug-resistant TB were registered, of which the highest concentration was reported from 2008 onward (p = 0.002). The municipalities with the largest numbers of indigenous individuals affected were São Gabriel da Cachoeira (93%), Itamarati (78.1%), and Santa Isabel do Rio Negro (70.1%). The future outlook for this region includes strengthening the TB control at the primary care level, by expanding diagnostic capabilities, access to treatment, research projects developed in collaboration with the Dr. Heitor Vieira Dourado Tropical Medicine Foundation .;Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (FMT-HVD).; and financing institutions, such as the project for the expansion of the Clinical Research Center and the creation of a hospital ward for individuals with transmissible respiratory diseases, including TB.
结核病是导致全球数百万人发病和死亡的主要传染病之一。巴西是承担全球80%结核病负担的22个国家之一。巴西发病率最高的地区是亚马孙州和里约热内卢州。本研究的目的是描述亚马孙州结核病的时间分布情况。2001年至2011年期间，亚马孙州报告了28198例结核病病例，分布在62个市，首府马瑙斯报告的病例集中度最高（68.7%）。结核病在15至34岁的男性（59.3%）中更为普遍，这些男性以帕尔多种族/肤色为主（64.7%），且患有肺结核（84.3%）。在此期间，登记了81例耐多药结核病病例，其中最高集中度是从2008年起报告的（p = 0.002）。受影响的土著居民人数最多的市是卡舒埃拉河畔圣加布里埃尔（93%）、伊塔马拉蒂（78.1%）和里奥内格罗河畔圣伊莎贝尔（70.1%）。该地区的未来展望包括通过扩大诊断能力、获得治疗的机会以及与埃托尔·维埃拉·多拉多热带医学基金会合作开展的研究项目，在初级保健层面加强结核病控制。；埃托尔·维埃拉·多拉多热带医学基金会（FMT - HVD）。；以及金融机构，如临床研究中心扩建项目和为包括结核病在内的可传播呼吸道疾病患者设立医院病房。
