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[阻塞性睡眠呼吸暂停综合征患者的耳鼻喉病理检查结果有多常见?]

[How frequent are pathologic ENT findings in patients with obstructive sleep apnea syndrome?].

作者信息

Mayer-Brix J, Müller-Marschhausen U, Becker H, Peter J H

机构信息

Klinik für Hals-Nasen-Ohrenheilkunde, Philipps-Universität Marburg.

出版信息

HNO. 1989 Dec;37(12):511-6.

PMID:2606743
Abstract

Several studies have been reported suggesting a relationship between pharyngeal obstruction due to ENT pathology and the sleep apnea syndrome (SAS). To determine the incidence of pathological ENT findings that may present symptoms similar to SAS, we performed ENT examination, fiberoptic nasopharyngoscopy, rhinomanometry and partial audiometry and electronystagmography in 431 patients who had undergone polysomnography for clinically suspected SAS. 336 patients were referred for ENT examination; 95 patients had some kind of ENT disease and therapy before polysomnography. In the first group 31% showed one or more pathological ENT finding (ears 9%, nasopharynx 2%, nose 19%, oropharynx 5%, larynx 5%, neck 1%); 10.5% had pathology in two regions and 0.7% in three regions. An ENT operation was indicated in 23%, usually for nasal obstruction. ENT findings included chronic otitis media, adenoids, enlargement of lingual tonsil and vocal cord pathology, but no patient had a malignant tumor or severe pharyngeal obstruction. We conclude that severe anatomical abnormalities or dysplastic syndromes are rare; only 2 SAS patients had acromegaly due to hypophyseal adenoma and 1 patient without SAS had craniofacial dysplasia. However, ENT examination frequently revealed severe nasal obstruction due to septal deviation, polyposis or adenoids. These findings emphasize the need for ENT examination and therapy before application of CPAP (continuous positive air pressure) therapy.

摘要

已有多项研究报告表明,耳鼻喉科病理导致的咽阻塞与睡眠呼吸暂停综合征(SAS)之间存在关联。为了确定可能出现类似于SAS症状的耳鼻喉科病理发现的发生率,我们对431例因临床怀疑患有SAS而接受多导睡眠图检查的患者进行了耳鼻喉科检查、纤维鼻咽镜检查、鼻阻力测量、部分听力测定和眼震电图检查。336例患者被转诊进行耳鼻喉科检查;95例患者在进行多导睡眠图检查之前患有某种耳鼻喉科疾病并接受过治疗。在第一组中,31%的患者有一项或多项耳鼻喉科病理发现(耳部9%、鼻咽部2%、鼻部19%、口咽部5%、喉部5%、颈部1%);10.5%的患者在两个区域有病理改变,0.7%的患者在三个区域有病理改变。23%的患者需要进行耳鼻喉科手术,通常是因为鼻阻塞。耳鼻喉科检查结果包括慢性中耳炎、腺样体、舌扁桃体肿大和声带病变,但没有患者患有恶性肿瘤或严重的咽阻塞。我们得出结论,严重的解剖异常或发育异常综合征很少见;只有2例SAS患者因垂体腺瘤患有肢端肥大症,1例非SAS患者患有颅面发育异常。然而,耳鼻喉科检查经常发现由于鼻中隔偏曲、息肉或腺样体导致的严重鼻阻塞。这些发现强调了在应用持续气道正压通气(CPAP)治疗之前进行耳鼻喉科检查和治疗的必要性。

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