与爱泼斯坦-巴尔病毒感染相关的低分化胃癌的缓慢进展：12年随访

Slow Progression of Poorly Differentiated Gastric Carcinoma Associated with Epstein-Barr Virus Infection: 12-year Follow-up.

作者信息

Yoza Rina, Ueda Yoshihide, Sakuma Yojiro, Minami Naoki, Takahashi Ken, Minamiguchi Sachiko, Haga Hironori, Chiba Tsutomu

机构信息

Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Japan.

出版信息

Intern Med. 2015;54(12):1505-8. doi: 10.2169/internalmedicine.54.4214. Epub 2015 Jun 15.

DOI:10.2169/internalmedicine.54.4214

PMID:26073239

Abstract

Epstein-Barr virus (EBV)-associated gastric carcinoma accounts for nearly 10% of all gastric carcinomas and has distinct demographic, clinical and pathological features compared with EBV-negative gastric carcinoma. We herein report the case of a patient with EBV-associated gastric carcinoma followed up for 12 years during the natural course of the disease. The appearance of the tumor on gastroscopy and computed tomography gradually changed, and the size of the lesion increased very slowly during the 12 years, without metastasis. The present case indicates that some EBV-associated gastric carcinomas progress very slowly.

摘要

爱泼斯坦-巴尔病毒（EBV）相关的胃癌占所有胃癌的近10%，与EBV阴性的胃癌相比，具有不同的人口统计学、临床和病理特征。我们在此报告一例EBV相关胃癌患者，在疾病自然进程中随访了12年。在这12年中，胃镜检查和计算机断层扫描显示肿瘤外观逐渐改变，病变大小增长非常缓慢，且无转移。本病例表明，一些EBV相关的胃癌进展非常缓慢。