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日本银屑病关节炎的患病率及临床特征

Prevalence and Clinical Characteristics of Psoriatic Arthritis in Japan.

作者信息

Ohara Yuri, Kishimoto Mitsumasa, Takizawa Naoho, Yoshida Kazuki, Okada Masato, Eto Hikaru, Deshpande Gautam A, Ritchlin Christopher T, Tanaka Atsushi, Higashiyama Mari, Matsui Kazuo, Tsuji Shigeyoshi

机构信息

From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.

出版信息

J Rheumatol. 2015 Aug;42(8):1439-42. doi: 10.3899/jrheum.141598. Epub 2015 Jun 15.

DOI:10.3899/jrheum.141598
PMID:26077408
Abstract

OBJECTIVE

To investigate the prevalence of psoriatic arthritis (PsA) in Japanese patients with psoriasis.

METHODS

A multicenter, noninterventional, retrospective cross-sectional study was conducted at 3 tertiary care centers in Japan. PsA was diagnosed by rheumatologists based on clinical findings. Prevalence of PsA, clinical characteristics, comorbidities, and treatment patterns were examined.

RESULTS

PsA was identified in 431 of 3021 patients with psoriasis, with a mean prevalence of 14.3% (range, 8.8-20.4%). No large differences between these results and previous reports from Western countries were observed in arthritis distribution, skin disease type, or treatment selection.

CONCLUSION

The prevalence of PsA in patients with psoriasis in Japan approaches 20% in some areas, similar to that observed in Western countries, and is higher than previously reported in Asia. Clinical features including age, sex, age at onset, and manifestation patterns were also similar to those reported in the West.

摘要

目的

调查日本银屑病患者中银屑病关节炎(PsA)的患病率。

方法

在日本的3家三级医疗中心进行了一项多中心、非干预性、回顾性横断面研究。风湿科医生根据临床发现诊断PsA。对PsA的患病率、临床特征、合并症和治疗模式进行了检查。

结果

在3021例银屑病患者中,有431例被诊断为PsA,平均患病率为14.3%(范围为8.8%-20.4%)。在关节炎分布、皮肤病类型或治疗选择方面,这些结果与西方国家以前的报告没有很大差异。

结论

日本银屑病患者中PsA的患病率在某些地区接近20%,与西方国家观察到的情况相似,且高于亚洲以前的报告。包括年龄、性别、发病年龄和表现模式在内的临床特征也与西方报告的相似。

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