Zeller S, Abel T, Rojas-Vega S, Foitschik T, Strueder H K
Institute of Movement and Neurosciences, German Sport University Cologne,Cologne, Germany.
European Research Group in Disability Sport.
Spinal Cord. 2015 Nov;53(11):791-4. doi: 10.1038/sc.2015.94. Epub 2015 Jun 16.
A prospective cohort with acute tetraplegia.
The purpose of this study was to investigate acute changes in serum brain-derived neurotrophic factor (BDNF) concentrations in tetraplegic spinal cord-injured (SCI) athletes during a typical training session of wheelchair rugby.
German Sport University Cologne, Cologne, Germany.
Eleven male SCI (AIS A and B) athletes completed a 90-min training session: The warm-up period included continuous pushing, submaximal increasing sprints and agility drills. The main training section comprised ball handling, passing drills, scrimmage activity and tactical practice. At the end of the training session, the athletes did moderate continuous pushing as a short cool-down. Venous blood samples were taken at rest before exercise, after the warm-up period and immediately following the first part of the main training section. Serum was pipetted after 30 min of blood sample resting and a subsequent centrifugation. BDNF concentrations were measured using an enzyme immunoassay ELISA kit.
Heart rate (P < 0.01) and lactate (P = 0.04 and P < 0.01) concentration differed significantly in warm-up and main training part in comparison with basal values at rest. At rest, BDNF concentrations were 33.2 ± 21.6 ng ml(-1), after warm up 31.9 ± 18.9 ng ml(-1) and after the training session 29.9 ± 11 ng ml(-1), without significant differences (P > 0.05).
A typical wheelchair rugby training session does not affect basal serum BDNF concentration in elite SCI athletes. In comparison with concentrations previously reported in healthy subjects, the current values at rest were slightly higher or rather at the upper limit.
一项针对急性四肢瘫痪患者的前瞻性队列研究。
本研究旨在调查脊髓损伤（SCI）的四肢瘫痪运动员在轮椅橄榄球典型训练期间血清脑源性神经营养因子（BDNF）浓度的急性变化。
德国科隆体育大学，德国科隆。
11名男性SCI（AIS A和B级）运动员完成了一次90分钟的训练课程：热身阶段包括持续推车、次最大强度递增冲刺和敏捷性训练。主要训练部分包括控球、传球训练、混战活动和战术练习。训练课程结束时，运动员进行适度的持续推车作为简短的放松活动。在运动前休息时、热身期后以及主要训练部分的第一部分结束后立即采集静脉血样。血样静置30分钟后进行离心，然后吸取血清。使用酶免疫测定ELISA试剂盒测量BDNF浓度。
与休息时的基础值相比，热身和主要训练部分的心率（P < 0.01）和乳酸浓度（P = 0.04和P < 0.01）有显著差异。休息时，BDNF浓度为33.2 ± 21.6 ng/ml，热身后为31.9 ± 18.9 ng/ml，训练课程后为29.9 ± 11 ng/ml，无显著差异（P > 0.05）。
典型的轮椅橄榄球训练课程不会影响精英SCI运动员的基础血清BDNF浓度。与先前报道的健康受试者浓度相比，目前休息时的值略高或处于上限。
