Kerfant N, Bardin T, Roulot E
Service de Chirurgie Plastique, Reconstructrice et Esthétique, CHRU de Brest. Hôpital La Cavale Blanche, 29609 Brest, Cedex France.
Fédération de Rhumatologie, Hôpital Lariboisière, 2 Rue Ambrois-Paré, Paris, France.
J Hand Microsurg. 2015 Jun;7(1):233-5. doi: 10.1007/s12593-015-0185-3. Epub 2015 May 19.
Giant-cell tumors of the tendon sheath correspond to a localized form of pigmented villonodular synovitis. GCTTS typically occur in the hand where they represent the second most common type of soft tissue tumors after synovial ganglions. The etiology of giant cell tumors of the tendon sheath is unknown. Pathogenetic theories have included inflammatory process, trauma, immune mechanisms, neoplasia. Giant cell tumors usually present as a solitary and firm slow-growing nodular lesion, which affects the volar aspect of the hand. Multifocal lesions are rarely described in the literature and commonly involve the same finger or the volar aspect of different fingers. We report a rare case of three separate GCT occurring on both aspects of the hand thus raising the question of their etiology.
腱鞘巨细胞瘤相当于色素沉着绒毛结节性滑膜炎的一种局限性形式。腱鞘巨细胞瘤通常发生于手部，是继滑膜囊肿之后手部第二常见的软组织肿瘤类型。腱鞘巨细胞瘤的病因尚不清楚。发病机制理论包括炎症过程、创伤、免疫机制、肿瘤形成。巨细胞瘤通常表现为单个、质地硬、生长缓慢的结节性病变，累及手掌面。文献中很少描述多灶性病变，多灶性病变通常累及同一手指或不同手指的掌面。我们报告1例罕见病例，手部两侧出现3个独立的腱鞘巨细胞瘤，从而引发了其病因的问题。
