Shintani Ryo, Kurata Hiroki, Nozaki Kyoko
Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Chem Commun (Camb). 2015 Jul 21;51(57):11378-81. doi: 10.1039/c5cc04172d.
Rhodium-catalyzed intramolecular alkynylsilylation of alkynes is described. The reaction proceeds through syn-insertion by a cationic rhodium/triarylphosphine catalyst, representing the first alkynylsilylation of alkynes via the cleavage of a C(sp)-Si bond by transition-metal catalysis. A highly enantioselective variant is also described for the creation of a silicon stereogenic center.
本文描述了铑催化的炔烃分子内炔基硅基化反应。该反应通过阳离子铑/三芳基膦催化剂进行顺式插入，这是过渡金属催化通过C(sp)-Si键裂解实现的首例炔烃炔基硅基化反应。本文还描述了一种用于构建硅立体中心的高对映选择性变体反应。
