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铑催化的三芳基甲醇与内炔烃通过连续的C-H和C-C键裂解进行氧化偶联反应。

Rhodium-catalyzed oxidative coupling of triarylmethanols with internal alkynes via successive C-H and C-C bond cleavages.

作者信息

Uto Toshihiko, Shimizu Masaki, Ueura Kenji, Tsurugi Hayato, Satoh Tetsuya, Miura Masahiro

机构信息

Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.

出版信息

J Org Chem. 2008 Jan 4;73(1):298-300. doi: 10.1021/jo7022087. Epub 2007 Dec 5.

DOI:10.1021/jo7022087
PMID:18052297
Abstract

The rhodium-catalyzed oxidative coupling of triarylmethanols with internal alkynes effectively proceeds in a 1:2 manner via cleavage of C-H and C-C bonds to produce the corresponding naphthalene derivatives. Addition of tri- or tetraphenylcyclopentadiene as a ligand is crucial for the reaction to occur efficiently.

摘要

铑催化的三芳基甲醇与内炔的氧化偶联反应通过C-H键和C-C键的断裂以1:2的比例有效地进行，生成相应的萘衍生物。添加三苯基或四苯基环戊二烯作为配体对于反应的高效进行至关重要。

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