从健康成人人类成纤维细胞中生成诱导多能干细胞系HEL47.2。
Generation of iPSC line HEL47.2 from healthy human adult fibroblasts.
作者信息
Trokovic Ras, Weltner Jere, Otonkoski Timo
机构信息
Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Centre, University of Helsinki, Helsinki, Finland.
Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Centre, University of Helsinki, Helsinki, Finland.
出版信息
Stem Cell Res. 2015 Jul;15(1):263-5. doi: 10.1016/j.scr.2015.05.013. Epub 2015 Jun 2.
PMID:26096151
Abstract
Human iPSC line HEL47.2 was generated from healthy 83-year old male dermal fibroblasts using non-integrative reprogramming method. Reprogramming factors Oct3/4, Sox2, Klf4, and cMyc were delivered using Sendai viruses.
摘要
人诱导多能干细胞系HEL47.2是使用非整合重编程方法从一名83岁健康男性的真皮成纤维细胞中产生的。重编程因子Oct3/4、Sox2、Klf4和cMyc通过仙台病毒导入。
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