Graduate Program in Public Health, Eastern Virginia Medical School, Norfolk, Virginia.
J Am Geriatr Soc. 2015 Jul;63(7):1401-6. doi: 10.1111/jgs.13477. Epub 2015 Jun 11.
To examine the association between self-reported sleep duration and osteoporosis in a national sample of the U.S. elderly population.
Population-based cross-sectional study.
Four-year National Health and Nutrition Examination Survey data from two survey cycles between 2005-06 and 2007-08.
Men and women aged 50 and older with data in the surveys and medical examination data files (N = 5,288).
Osteoporosis diagnosis was based on bone mineral density measurement and self-report. Sleep duration was ascertained from the sleep survey. Simple and multiple logistic regression models were used to evaluate the association between these two factors.
Shorter sleep duration (<6 hours) was found to be significantly associated with osteoporosis after adjusting for potential covariates (odds ratio (OR) = 1.59, 95% confidence interval (CI) = 1.07-2.37). After stratifying according to age group, this association remained significant (OR = 1.80, 95% CI = 1.20-2.68) only in the older age group (>65).
These results underscore the possible linkage between sleep and osteoporosis and the need for additional research on this topic.
在美国老年人群体的全国样本中,研究自我报告的睡眠时间与骨质疏松症之间的关联。
基于人群的横断面研究。
两个调查周期(2005-06 年至 2007-08 年)的四年国家健康和营养调查数据。
有调查和体检数据文件的 50 岁及以上男性和女性(N=5288)。
骨质疏松症的诊断基于骨密度测量和自我报告。睡眠时间是从睡眠调查中确定的。采用简单和多逻辑回归模型评估这两个因素之间的关联。
调整潜在混杂因素后,较短的睡眠时间(<6 小时)与骨质疏松症显著相关(优势比(OR)=1.59,95%置信区间(CI)=1.07-2.37)。按年龄组分层后,这种关联仅在年龄较大组(>65 岁)中仍然显著(OR=1.80,95%CI=1.20-2.68)。
这些结果强调了睡眠和骨质疏松症之间可能存在联系,需要对此主题进行更多研究。