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一维动脉血流建模数值格式的基准研究。

A benchmark study of numerical schemes for one-dimensional arterial blood flow modelling.

作者信息

Boileau Etienne, Nithiarasu Perumal, Blanco Pablo J, Müller Lucas O, Fossan Fredrik Eikeland, Hellevik Leif Rune, Donders Wouter P, Huberts Wouter, Willemet Marie, Alastruey Jordi

机构信息

Zienkiewicz Centre for Computational Engineering, College of Engineering, Swansea University, Swansea, SA2 8PP, UK.

National Laboratory for Scientific Computing, LNCC/MCTI, Av. Getúlio Vargas 333, Petrópolis, Rio de Janeiro 25651-075, Brazil.

出版信息

Int J Numer Method Biomed Eng. 2015 Oct;31(10). doi: 10.1002/cnm.2732. Epub 2015 Jul 3.

Abstract

Haemodynamical simulations using one-dimensional (1D) computational models exhibit many of the features of the systemic circulation under normal and diseased conditions. Recent interest in verifying 1D numerical schemes has led to the development of alternative experimental setups and the use of three-dimensional numerical models to acquire data not easily measured in vivo. In most studies to date, only one particular 1D scheme is tested. In this paper, we present a systematic comparison of six commonly used numerical schemes for 1D blood flow modelling: discontinuous Galerkin, locally conservative Galerkin, Galerkin least-squares finite element method, finite volume method, finite difference MacCormack method and a simplified trapezium rule method. Comparisons are made in a series of six benchmark test cases with an increasing degree of complexity. The accuracy of the numerical schemes is assessed by comparison with theoretical results, three-dimensional numerical data in compatible domains with distensible walls or experimental data in a network of silicone tubes. Results show a good agreement among all numerical schemes and their ability to capture the main features of pressure, flow and area waveforms in large arteries. All the information used in this study, including the input data for all benchmark cases, experimental data where available and numerical solutions for each scheme, is made publicly available online, providing a comprehensive reference data set to support the development of 1D models and numerical schemes.

摘要

使用一维(1D)计算模型进行的血流动力学模拟展现了正常和患病条件下体循环的许多特征。近期对验证一维数值方案的关注促使了替代实验装置的开发以及三维数值模型的使用,以获取体内不易测量的数据。在迄今为止的大多数研究中,仅测试了一种特定的一维方案。在本文中,我们对用于一维血流建模的六种常用数值方案进行了系统比较:间断伽辽金法、局部守恒伽辽金法、伽辽金最小二乘有限元法、有限体积法、有限差分麦科马克法和简化梯形法则法。在一系列六个复杂度逐渐增加的基准测试案例中进行了比较。通过与理论结果、具有可扩张壁的兼容域中的三维数值数据或硅胶管网络中的实验数据进行比较,评估了数值方案的准确性。结果表明,所有数值方案之间具有良好的一致性,并且它们能够捕捉大动脉中压力、流量和面积波形的主要特征。本研究中使用的所有信息,包括所有基准案例的输入数据、可用的实验数据以及每种方案的数值解,都在网上公开提供,提供了一个全面的参考数据集,以支持一维模型和数值方案的开发。

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