Solorzano Sendy, Ramirez Renán, Cabada Miguel M, Montoya Manuel, Cazorla Ernesto
Departamento de Medicina, Hospital Regional del Cusco, Cusco, Perú
Departamento de Medicina Interna, University of Texas Medical Branch, Galveston, Texas, EE. UU.
Rev Peru Med Exp Salud Publica. 2015 Jan-Mar;32(1):187-90.
Disseminated sporotrichosis is a rare presentation of this mycosis. Although it has been described in immunocompetent individuals, there is often T cell-mediated immune compromise. We report the case of a woman with uncontrolled Type 2 diabetes who developed disseminated cutaneous sporotrichosis. The course of the disease presented several complications including hepatitis secondary to itraconazole and knee arthritis with culture positive for Sporothrix schenckii during treatment with saturated solution of potassium iodide. The case discussion includes aspects of the pathogenesis of disseminated sporotrichosis and management of the infection and its complications.
播散性孢子丝菌病是这种真菌病的一种罕见表现形式。尽管在免疫功能正常的个体中也有相关报道，但通常存在T细胞介导的免疫功能受损情况。我们报告了一例2型糖尿病控制不佳的女性发生播散性皮肤孢子丝菌病的病例。该疾病过程出现了多种并发症，包括伊曲康唑继发的肝炎，以及在碘化钾饱和溶液治疗期间膝关节关节炎且申克孢子丝菌培养阳性。病例讨论包括播散性孢子丝菌病的发病机制、感染及其并发症的处理等方面。
