Narayanasamy Ganesh, Zalman Travis, Ha Chul S, Papanikolaou Niko, Stathakis Sotirios
University of Texas Health Science Center at San Antonio.
J Appl Clin Med Phys. 2015 May 8;16(3):5427. doi: 10.1120/jacmp.v16i3.5427.
The purpose of this study is to evaluate the use of the Dosimetry Check system for patient-specific IMRT QA. Typical QA methods measure the dose in an array dosimeter surrounded by homogenous medium for which the treatment plan has been recomputed. With the Dosimetry Check system, fluence measurements acquired on a portal dosimeter is applied to the patient's CT scans. Instead of making dose comparisons in a plane, Dosimetry Check system produces isodose lines and dose-volume histograms based on the planning CT images. By exporting the dose distribution from the treatment planning system into the Dosimetry Check system, one is able to make a direct comparison between the calculated dose and the planned dose. The versatility of the software is evaluated with respect to the two IMRT techniques - step and shoot and volumetric arc therapy. The system analyzed measurements made using EPID, PTW seven29, and IBA MatriXX, and an intercomparison study was performed. Plans from patients previously treated at our institution with treated anatomical site on brain, head & neck, liver, lung, and prostate were analyzed using Dosimetry Check system for any anatomical site dependence. We have recommendations and possible precautions that may be necessary to ensure proper QA with the Dosimetry Check system.
本研究的目的是评估剂量学检查系统用于患者特异性调强放射治疗(IMRT)质量保证(QA)的情况。典型的QA方法是在被均匀介质包围的阵列剂量仪中测量剂量,针对该介质重新计算治疗计划。使用剂量学检查系统时,在门静脉剂量仪上获取的注量测量值被应用于患者的CT扫描。剂量学检查系统不是在一个平面上进行剂量比较,而是基于计划CT图像生成等剂量线和剂量体积直方图。通过将治疗计划系统中的剂量分布导出到剂量学检查系统中,能够直接比较计算剂量和计划剂量。针对两种IMRT技术——静态调强和容积弧形调强,对该软件的通用性进行了评估。该系统分析了使用电子射野影像装置(EPID)、PTW seven29和IBA MatriXX进行的测量,并开展了一项相互比较研究。使用剂量学检查系统分析了我院之前治疗过的患者的计划,这些患者的治疗解剖部位包括脑、头颈部、肝脏、肺和前列腺,以研究是否存在任何解剖部位依赖性。我们有一些建议和可能需要采取的预防措施,以确保使用剂量学检查系统进行适当的QA。