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英国外照射放射治疗中的体内剂量测定:当前及未来应用

In vivo dosimetry in UK external beam radiotherapy: current and future usage.

作者信息

MacDougall Niall D, Graveling Michael, Hansen Vibeke N, Brownsword Kevin, Morgan Andrew

机构信息

1 Radiotherapy Physics, St Bartholomew's Hospital, London, UK.

2 Radiotherapy Department Northamptonshire Centre for Oncology, Northampton, UK.

出版信息

Br J Radiol. 2017 Apr;90(1072):20160915. doi: 10.1259/bjr.20160915. Epub 2017 Feb 16.

Abstract

OBJECTIVE

Towards Safer Radiotherapy recommended that radiotherapy (RT) centres should have protocols in place for in vivo dosimetry (IVD) monitoring at the beginning of patient treatment courses (Donaldson S. Towards safer radiotherapy. R Coll Radiol 2008). This report determines IVD implementation in the UK in 2014, the methods used and makes recommendations on future use.

METHODS

Evidence from peer-reviewed journals was used in conjunction with the first survey of UK RT centre IVD practice since the publication of Towards Safer Radiotherapy. In March 2014, profession-specific questionnaires were sent to radiographer, clinical oncologist and physics staff groups in each of the 66 UK RT centres.

RESULTS

Response rates from each group were 74%, 45% and 74%, respectively. 73% of RT centres indicated that they performed IVD. Diodes are the most popular IVD device. Thermoluminescent dosimeter (TLD) is still in use in a number of centres but not as a sole modality, being used in conjunction with diodes and/or electronic portal imaging device (EPID). The use of EPID dosimetry is increasing and is considered of most potential value for both geometric and dosimetric verification.

CONCLUSION

Owing to technological advances, such as electronic data transfer, independent monitor unit checking and daily image-guided radiotherapy, the overall risk of adverse treatment events in RT has been substantially reduced. However, the use of IVD may prevent a serious radiation incident. Point dose IVD is not considered suited to the requirements of verifying advanced RT techniques, leaving EPID dosimetry as the current modality likely to be developed as a future standard. Advances in knowledge: An updated perspective on UK IVD use and provision of professional guidelines for future implementation.

摘要

目的

《迈向更安全的放射治疗》建议放射治疗(RT)中心应制定在患者治疗疗程开始时进行体内剂量测定(IVD)监测的方案(唐纳森S.迈向更安全的放射治疗。英国皇家放射学院杂志2008年)。本报告确定了2014年英国IVD的实施情况、所使用的方法,并对其未来应用提出建议。

方法

自《迈向更安全的放射治疗》发表以来,结合对英国RT中心IVD实践的首次调查,使用了同行评审期刊中的证据。2014年3月,向英国66个RT中心的放射技师、临床肿瘤学家和物理工作人员群体发送了针对特定专业的问卷。

结果

每个群体的回复率分别为74%、45%和74%。73%的RT中心表示他们进行IVD。二极管是最常用的IVD设备。热释光剂量计(TLD)仍在一些中心使用,但不作为唯一方式,而是与二极管和/或电子门静脉成像设备(EPID)结合使用。EPID剂量测定的使用正在增加,并且被认为在几何和剂量验证方面最具潜在价值。

结论

由于电子数据传输、独立监测单元检查和每日图像引导放射治疗等技术进步,RT中不良治疗事件的总体风险已大幅降低。然而,IVD的使用可能预防严重的放射事件。点剂量IVD被认为不适合验证先进RT技术的要求,使得EPID剂量测定成为当前可能发展为未来标准的方式。知识进展:关于英国IVD使用的最新观点以及为未来实施提供专业指南。

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