Michaeli Simon, Fromm Hillel
Department of Molecular Biology and Ecology of Plants, Faculty of Life Sciences, Tel Aviv University , Tel Aviv, Israel.
Front Plant Sci. 2015 Jun 9;6:419. doi: 10.3389/fpls.2015.00419. eCollection 2015.
γ-Aminobutyric acid (GABA) is a non-proteinogenic amino acid that is found in uni- and multi-cellular organisms and is involved in many aspects of plant life cycle. GABA metabolism occurs by the action of evolutionary conserved enzymes that constitute the GABA shunt, bypassing two steps of the TCA cycle. The central position of GABA in the interface between plant carbon and nitrogen metabolism is well established. In parallel, there is evidence to support a role for GABA as a signaling molecule in plants. Here we cover some of the recent findings on GABA metabolism and signaling in plants and further suggest that the metabolic and signaling aspects of GABA may actually be inseparable.
γ-氨基丁酸（GABA）是一种非蛋白质ogenic氨基酸，存在于单细胞和多细胞生物中，并参与植物生命周期的许多方面。GABA代谢通过构成GABA分流的进化保守酶的作用发生，绕过了三羧酸循环的两个步骤。GABA在植物碳氮代谢界面中的核心地位已得到充分确立。同时，有证据支持GABA在植物中作为信号分子的作用。在这里，我们涵盖了一些关于植物中GABA代谢和信号传导的最新发现，并进一步表明GABA的代谢和信号传导方面实际上可能是不可分割的。
