Department of Plant Molecular Physiology, Faculty of Biological Sciences, University of Wrocław, Kanonia 6/8, 50-328 Wrocław, Poland.
Int J Mol Sci. 2024 Oct 6;25(19):10749. doi: 10.3390/ijms251910749.
GABA (gamma-aminobutyric acid) is an amino acid whose numerous regulatory functions have been identified in animal organisms. More and more research indicate that in plants, this molecule is also involved in controlling basic growth and development processes. As recent studies have shown, GABA plays an essential role in triggering plant resistance to unfavorable environmental factors, which is particularly important in the era of changing climate. The main sources of GABA in plant cells are glutamic acid, converted in the GABA shunt pathway, and polyamines subjected to oxidative degradation. The action of GABA is often related to the activity of other messengers, including phytohormones, polyamines, NO, HO, or melatonin. GABA can function as an upstream or downstream element in the signaling pathways of other regulators, acting synergistically or antagonistically with them to control cellular processes. Understanding the role of GABA and its interactions with other signaling molecules may be important for developing crop varieties with characteristics that enable adaptation to a changing environment.
γ-氨基丁酸（GABA）是一种氨基酸，其在动物机体中的众多调节功能已被确定。越来越多的研究表明，在植物中，该分子也参与控制基本的生长和发育过程。正如最近的研究表明，GABA 在触发植物对不利环境因素的抗性方面起着至关重要的作用，这在气候变化的时代尤为重要。植物细胞中 GABA 的主要来源是谷氨酸，其在 GABA 分流途径中转化，以及经过氧化降解的多胺。GABA 的作用通常与其他信使（包括植物激素、多胺、NO、HO 或褪黑素）的活性有关。GABA 可以作为其他调节剂信号通路中的上游或下游元件，与它们协同或拮抗作用以控制细胞过程。了解 GABA 的作用及其与其他信号分子的相互作用可能对开发具有适应不断变化环境的特征的作物品种很重要。
