Silva-Carvalho Ricardo, Baltazar Fátima, Almeida-Aguiar Cristina
Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710-057 Braga, Portugal ; ICVS/3B's, PT Government Associate Laboratory, Guimarães, 4710-057 Braga, Portugal.
Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), Biology Department, University of Minho, 4710-057 Braga, Portugal.
Evid Based Complement Alternat Med. 2015;2015:206439. doi: 10.1155/2015/206439. Epub 2015 May 27.
The health industry has always used natural products as a rich, promising, and alternative source of drugs that are used in the health system. Propolis, a natural resinous product known for centuries, is a complex product obtained by honey bees from substances collected from parts of different plants, buds, and exudates in different geographic areas. Propolis has been attracting scientific attention since it has many biological and pharmacological properties, which are related to its chemical composition. Several in vitro and in vivo studies have been performed to characterize and understand the diverse bioactivities of propolis and its isolated compounds, as well as to evaluate and validate its potential. Yet, there is a lack of information concerning clinical effectiveness. The goal of this review is to discuss the potential of propolis for the development of new drugs by presenting published data concerning the chemical composition and the biological properties of this natural compound from different geographic origins.
健康产业一直将天然产物作为卫生系统中使用的丰富、有前景的替代药物来源。蜂胶是一种几个世纪以来为人所知的天然树脂产品，是蜜蜂从不同地理区域的不同植物部分、芽和分泌物中采集的物质所获得的复杂产物。由于蜂胶具有许多与其化学成分相关的生物学和药理学特性，它一直吸引着科学界的关注。已经进行了多项体外和体内研究，以表征和了解蜂胶及其分离化合物的多种生物活性，以及评估和验证其潜力。然而，关于临床疗效的信息却很匮乏。本综述的目的是通过展示有关这种来自不同地理来源的天然化合物的化学成分和生物学特性的已发表数据，来讨论蜂胶在新药开发方面的潜力。
