Laboratório de Imunologia e Biologia Molecular, Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, Brazil.
Programa de Pós-graduação em Processos Interativos de Órgãos e Sistemas, Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, Brazil.
J Sci Food Agric. 2020 Mar 15;100(4):1369-1382. doi: 10.1002/jsfa.10024. Epub 2019 Dec 14.
Propolis is a resinous substance composed of a mixture of different plant parts and molecules secreted by bees. Chemically, it is defined as a complex matrix containing biologically active molecules with antibacterial, antifungal, antiviral, antiparasitic, hepatoprotective, and immunomodulatory activities. It is widely employed in cosmetic formulations and pharmaceutical products and is one of the most widely used natural products. However, the effects and strength of these biological activities depend on the chemical profile and composition of each propolis type. This composition is associated with the diversity of local flora, the place and period of collection, and the genetics of the bees. In this context, the objective of this review was to investigate the biological, chemical, and microbiological properties of propolis. A technological prospection was also performed on patents for products designed to be used in animal health. Our investigation shows that the literature contains diverse studies dedicated to comparing and describing the composition and therapeutic properties of propolis. These studies demonstrate the potential biological use of propolis in veterinary medicine, showing the applications of propolis extracts in different formulations. However, there are a low number of propolis-based veterinary products with a registered patent. Thus, the development of products based on propolis is a promising market to be exploited. © 2019 Society of Chemical Industry.
蜂胶是一种由不同植物部分和蜜蜂分泌的分子混合而成的树脂状物质。从化学角度来看，它被定义为一种复杂的基质，其中包含具有抗菌、抗真菌、抗病毒、抗寄生虫、保肝和免疫调节活性的生物活性分子。它被广泛应用于化妆品配方和药品中，是使用最广泛的天然产品之一。然而，这些生物活性的效果和强度取决于每种蜂胶类型的化学特征和组成。这种组成与当地植物群的多样性、收集的地点和时间以及蜜蜂的遗传有关。在这种情况下，本综述的目的是研究蜂胶的生物学、化学和微生物学特性。还对旨在用于动物健康的产品专利进行了技术展望。我们的调查表明，文献中包含了许多致力于比较和描述蜂胶组成和治疗特性的研究。这些研究表明，蜂胶在兽医医学中有潜在的生物学用途，展示了蜂胶提取物在不同配方中的应用。然而，基于蜂胶的兽医产品的专利注册数量很少。因此，开发基于蜂胶的产品是一个有前途的市场。© 2019 英国化学学会。
