Tsang C W, Chan S F, Lee P P, Pang S F
Department of Applied Biology & Chemical Technology, Hong Kong Polytechnic.
Biochem Biophys Res Commun. 1989 Dec 29;165(3):1331-6. doi: 10.1016/0006-291x(89)92749-6.
The occurrence of 5-methoxytryptophol (5-MTL) in the quail retina was investigated by capillary column gas chromatography/mass spectrometry/selected ion monitoring using a deuterated internal standard. Based on ion intensity ratios in the mass spectra of pentafluoropropionyl and heptafluorobutyryl derivatives of 5-MTL and deuterated 5-MTL, 5-MTL was unequivocally identified in the quail retina. Similar to the circadian rhythm of retinal melatonin, retinal 5-MTL also exhibited a diurnal variation with high levels at mid-dark. However, no significant correlation between the diurnal levels of 5-MTL and melatonin was observed in the quail retina at mid-light or mid-dark.
