伴有甲状腺乳头状癌的马林-伦哈特综合征。

Marine-Lenhart syndrome with papillary thyroid carcinoma.

作者信息

Atmaca Hulusi, Çolak Ramis, Yazici Zihni Acar, Kefeli Mehmet, Tosun Fevziye Canbaz

机构信息

Department of Endocrinology and Metabolism, Ondokuz Mayis University Medical School, Samsun, Turkey.

Department of Microbiology, Recep Tayyip Erdogan University Medical School, Rize, Turkey.

出版信息

J Res Med Sci. 2015 Apr;20(4):412-5.

PMID:26110000

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4468460/

Abstract

Graves' disease with accompanying functioning nodules is known as Marine-Lenhart syndrome. Autonomously functioning thyroid nodules (AFTNs) also within Graves' thyroid tissue are almost always bening in nature. A 45-year-old man developed hyperthyroidism due to the coexistence of Graves' disease and AFTN. Total thyroidectomy was performed. The hyperfunctioning nodule with centrally hypoactive foci detected by technetium-99m thyroid scanning was histologically diagnosed as papillary thyroid carcinoma that was 2.5 cm in diameter. We report the presence of papillary thyroid carcinoma within AFTN in patients with Marine-Lenhart syndrome, which has not been reported so far.

摘要

伴有功能性结节的格雷夫斯病被称为马-伦综合征。格雷夫斯甲状腺组织内的自主功能性甲状腺结节（AFTN）本质上几乎总是良性的。一名45岁男性因格雷夫斯病和AFTN并存而出现甲状腺功能亢进。实施了全甲状腺切除术。通过锝-99m甲状腺扫描检测到的具有中央低活性灶的高功能结节经组织学诊断为直径2.5厘米的甲状腺乳头状癌。我们报告了马-伦综合征患者的AFTN内存在甲状腺乳头状癌，这在迄今为止尚未见报道。