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使用离散纵标法进行计算机断层扫描中的确定性吸收剂量估计。

Deterministic absorbed dose estimation in computed tomography using a discrete ordinates method.

作者信息

Norris Edward T, Liu Xin, Hsieh Jiang

机构信息

Nuclear Engineering, Missouri University of Science and Technology, Rolla, Missouri 65409.

GE Healthcare, Waukesha, Wisconsin 53188.

出版信息

Med Phys. 2015 Jul;42(7):4080-7. doi: 10.1118/1.4922000.

Abstract

PURPOSE

Organ dose estimation for a patient undergoing computed tomography (CT) scanning is very important. Although Monte Carlo methods are considered gold-standard in patient dose estimation, the computation time required is formidable for routine clinical calculations. Here, the authors instigate a deterministic method for estimating an absorbed dose more efficiently.

METHODS

Compared with current Monte Carlo methods, a more efficient approach to estimating the absorbed dose is to solve the linear Boltzmann equation numerically. In this study, an axial CT scan was modeled with a software package, Denovo, which solved the linear Boltzmann equation using the discrete ordinates method. The CT scanning configuration included 16 x-ray source positions, beam collimators, flat filters, and bowtie filters. The phantom was the standard 32 cm CT dose index (CTDI) phantom. Four different Denovo simulations were performed with different simulation parameters, including the number of quadrature sets and the order of Legendre polynomial expansions. A Monte Carlo simulation was also performed for benchmarking the Denovo simulations. A quantitative comparison was made of the simulation results obtained by the Denovo and the Monte Carlo methods.

RESULTS

The difference in the simulation results of the discrete ordinates method and those of the Monte Carlo methods was found to be small, with a root-mean-square difference of around 2.4%. It was found that the discrete ordinates method, with a higher order of Legendre polynomial expansions, underestimated the absorbed dose near the center of the phantom (i.e., low dose region). Simulations of the quadrature set 8 and the first order of the Legendre polynomial expansions proved to be the most efficient computation method in the authors' study. The single-thread computation time of the deterministic simulation of the quadrature set 8 and the first order of the Legendre polynomial expansions was 21 min on a personal computer.

CONCLUSIONS

The simulation results showed that the deterministic method can be effectively used to estimate the absorbed dose in a CTDI phantom. The accuracy of the discrete ordinates method was close to that of a Monte Carlo simulation, and the primary benefit of the discrete ordinates method lies in its rapid computation speed. It is expected that further optimization of this method in routine clinical CT dose estimation will improve its accuracy and speed.

摘要

目的

对接受计算机断层扫描(CT)的患者进行器官剂量估算是非常重要的。尽管蒙特卡罗方法在患者剂量估算中被视为金标准,但对于常规临床计算所需的计算时间非常可观。在此,作者引入一种确定性方法以更高效地估算吸收剂量。

方法

与当前的蒙特卡罗方法相比,估算吸收剂量的一种更有效方法是对线性玻尔兹曼方程进行数值求解。在本研究中,使用软件包Denovo对轴向CT扫描进行建模,该软件包使用离散纵标法求解线性玻尔兹曼方程。CT扫描配置包括16个X射线源位置、束准直器、平板滤过器和蝴蝶结滤过器。模体为标准的32 cm CT剂量指数(CTDI)模体。使用不同的模拟参数进行了四次不同的Denovo模拟,包括求积集数量和勒让德多项式展开阶数。还进行了一次蒙特卡罗模拟以对Denovo模拟进行基准测试。对Denovo方法和蒙特卡罗方法获得的模拟结果进行了定量比较。

结果

发现离散纵标法与蒙特卡罗方法的模拟结果差异较小,均方根差异约为2.4%。发现具有较高阶勒让德多项式展开的离散纵标法低估了模体中心附近(即低剂量区域)的吸收剂量。在作者的研究中,求积集8和一阶勒让德多项式展开的模拟被证明是最有效的计算方法。在个人计算机上,求积集8和一阶勒让德多项式展开的确定性模拟的单线程计算时间为21分钟。

结论

模拟结果表明,确定性方法可有效用于估算CTDI模体中的吸收剂量。离散纵标法的准确性接近蒙特卡罗模拟,离散纵标法的主要优点在于其快速的计算速度。预计在常规临床CT剂量估算中对该方法进行进一步优化将提高其准确性和速度。

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