Department of Perinatal Medicine, Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, Italy.
Department of Perinatal Medicine, Institute for Maternal and Child Health - IRCCS Burlo Garofolo, Trieste, Italy.
J Pediatr. 2015 Sep;167(3):568-71. doi: 10.1016/j.jpeds.2015.06.013. Epub 2015 Jul 3.
To compare growth, fat mass (FM), and fat-free mass in surgical infants vs matched controls at similar postconceptional age (PCA).
Anthropometric and body composition measurements by air-displacement plethysmography (PeaPod-Infant Body Composition System; LMI, Concord, California) were performed at the same PCA in 21 infants who received gastrointestinal surgery and in 21 controls matched for gestational age, birth weight, and sex.
Despite similar anthropometry at birth, postsurgical infants were shorter (50.4 [4.7] cm vs 53.2 [4.1] cm, P = .001), lighter (3516 [743] g vs 3946 [874] g, P < .001), and had lower FM content (%FM 14.8 [4.7]% vs 20.2 [5.8]%, P < .0001) than their peers at similar PCA (43 [4] weeks). All surgical infants but 1 (20/21) received parenteral nutrition (PN). Mean PN duration was 40 (30) days. Five infants in the control group received PN because of prematurity for 15 (9-30) days. Nine infants in the surgical group and 1 in the control group had PN-associated cholestasis.
Neonates having surgery for gastrointestinal diseases were shorter, had lower weight, and lower FM content than their peers, despite receiving more PN. Body composition evaluation and monitoring may help optimize growth in these newborns.
比较接受胃肠手术的婴儿与同期校正胎龄（PCA）匹配对照组婴儿的生长、脂肪量（FM）和去脂体重（FFM）。
通过空气置换体描仪（PeaPod-Infant Body Composition System；LMI，加利福尼亚州 Concord）在 21 例接受胃肠手术的婴儿和 21 例同期校正胎龄、出生体重和性别匹配的对照组婴儿中进行人体测量和身体成分测量。
尽管出生时的人体测量值相似，但手术后的婴儿更矮（50.4 [4.7]cm 比 53.2 [4.1]cm，P =.001），更轻（3516 [743]g 比 3946 [874]g，P <.001），FM 含量（%FM 14.8 [4.7]%比 20.2 [5.8]%，P <.0001）也低于同期 PCA 时的同龄人。除了 1 例（20/21）以外，所有手术婴儿均接受了肠外营养（PN）。PN 的平均持续时间为 40（30）天。对照组中有 5 例婴儿因早产而接受了 15（9-30）天的 PN。21 例手术组中有 9 例婴儿和 1 例对照组婴儿出现与 PN 相关的胆汁淤积。
尽管接受了更多的 PN，但患有胃肠疾病接受手术的新生儿比同龄人更矮、体重更轻、FM 含量更低。身体成分评估和监测可能有助于优化这些新生儿的生长。
