Lee Seung Eun, Choi Yoo Shin, Kim Mi Kyung, Oh Hyoung-Chul, Do Jae Hyuk
Department of Surgery, Chung-Ang University College of Medicine, Seoul, Korea.
Department of Pathology, Chung-Ang University College of Medicine, Seoul, Korea.
Korean J Hepatobiliary Pancreat Surg. 2015 May;19(2):75-7. doi: 10.14701/kjhbps.2015.19.2.75. Epub 2015 May 31.
Ovarian metastases represent about 3-5% of all ovarian malignancies. Most of these tumors originate in the digestive tract and cholangiocarcinoma rarely involves the ovary. A 60-year-old woman was admitted for the investigation of abdominal distension that had lasted 1 week. One and a half years prior, the patient had undergone choledochal cyst excision, Roux-en Y hepaticojejunostomy and cholecystectomy. Computed tomography scans of the abdomen revealed a papillary mass in the remnant distal common bile duct and enlargement of both ovaries with a huge amount of ascites. An explorative laparotomy disclosed no peritoneal seeding with resectable cholangiocarcinoma and bilateral ovarian mass. Pylorus-preserving pancreatoduodenectomy and bilateral salphingo-oophorectomy with hysterectomy were performed. Histologically, it was a well-differentiated adenocarcinoma and all surgical margins were free of tumor. Both ovarian masses were consistent with metastatic adenocarcinoma from the common bile duct. The patient received six cycles of postoperative adjuvant systemic chemotherapy, dying after 10 months due to pulmonary embolism.
卵巢转移瘤约占所有卵巢恶性肿瘤的3% - 5%。这些肿瘤大多起源于消化道,胆管癌很少累及卵巢。一名60岁女性因腹胀持续1周入院检查。1年半前,该患者接受了胆总管囊肿切除术、Roux-en Y肝空肠吻合术和胆囊切除术。腹部计算机断层扫描显示胆总管远端残余处有一个乳头状肿块,双侧卵巢增大并有大量腹水。剖腹探查未发现腹膜种植转移,胆管癌及双侧卵巢肿块均可切除。遂行保留幽门的胰十二指肠切除术及双侧输卵管卵巢切除术加子宫切除术。组织学检查显示为高分化腺癌,所有手术切缘均无肿瘤。双侧卵巢肿块均符合来自胆总管的转移性腺癌。患者接受了六个周期的术后辅助全身化疗,10个月后因肺栓塞死亡。