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比贾布尔(维杰亚普拉 - 北卡纳塔克邦)地区及其周边基孔肯雅热血清流行病学调查

Seroepidemiological Survey of Chikungunya in and Around the Regions of Bijapur (Vijayapura - North Karnataka).

作者信息

Mudurangaplar Bharath, Peerapur Basavaraj V

机构信息

PhD Scholar, Department of Microbiology, Shri B M Patil Medical College and Research Center, BLDE University , Bijapur, Karnataka, India .

Professor, Department of Microbiology, Raichur Institute of Medical Sciences , Raichur, India .

出版信息

J Clin Diagn Res. 2015 May;9(5):DC01-2. doi: 10.7860/JCDR/2015/12962.5867. Epub 2015 May 1.

DOI:10.7860/JCDR/2015/12962.5867
PMID:26155474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4484066/
Abstract

BACKGROUND

Chikungunya is a debilitating, non-fatal, mosquito borne viral fever caused by Chikungunya virus (CHIVA). The disease is transmitted to humans by the bite of Aedes aegypti and Aedes albopictus mosquitoes. Severe outbreaks of Chikungunya have been reported in several countries of Africa and Asia. Chikungunya fever is characterized by fever with sudden onset, arthralgia, rash, headache and myalgia. However, arthralgia is painful and long-lasting, affecting primarily the peripheral joints.

OBJECTIVES

To find out the prevalence of Chikungunya fever in and around the regions of Bijapur district.

MATERIALS AND METHODS

The study was conducted from April 2011 to December 2014. Five hundred serum samples were collected from cases with pyrexia and arthralgia. Serum samples were tested for Chikungunya antibodies by Chikungunya IgM ELISA.

RESULTS AND CONCLUSION

Out of 500 samples 33 samples were confirmed positive for Chikungunya IgM antibodies. The prevalence rate of Chikungunya was 6.6% with maximum number of cases in the year 2013 (8.5%) and age group 15 to 40 (8.3%). Females (6.9%) were more affected than males. Thus, continuous sero-epidomological surveillance is needed for the control of Chikungunya fever.

摘要

背景

基孔肯雅热是一种由基孔肯雅病毒(CHIVA)引起的使人衰弱的非致命性蚊媒病毒性发热疾病。该疾病通过埃及伊蚊和白纹伊蚊叮咬传播给人类。非洲和亚洲的几个国家都报告了基孔肯雅热的严重疫情。基孔肯雅热的特征为突然发热、关节痛、皮疹、头痛和肌痛。然而,关节痛疼痛且持久,主要影响外周关节。

目的

了解比贾布尔地区及周边地区基孔肯雅热的流行情况。

材料与方法

研究于2011年4月至2014年12月进行。从发热和关节痛患者中采集了500份血清样本。通过基孔肯雅IgM酶联免疫吸附测定法检测血清样本中的基孔肯雅抗体。

结果与结论

在500份样本中,有33份样本的基孔肯雅IgM抗体检测呈阳性。基孔肯雅热的患病率为6.6%,2013年病例数最多(8.5%),15至40岁年龄组患病率最高(8.3%)。女性(6.9%)比男性受影响更严重。因此,为控制基孔肯雅热,需要持续进行血清流行病学监测。

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