苔藓样特征与纤维化：咀嚼烟草所致口腔病变中的共存现象
Lichenoid Features and Fibrosis: Coexistence in Quid-induced Oral Lesions.
作者信息
Yanduri Sarita, Kumar Veerendra B, Suma S, Madhura M G
机构信息
Reader, Department of Oral and Maxillofacial Pathology, DA Pandu Memorial RV Dental College, CA 37, 24th Main, JP Nagar, 1st Phase Bengaluru 560078, Karnataka, India, Phone: +91-9886147555 e-mail:
Department of Oral and Maxillofacial Pathology, DA Pandu Memorial RV Dental College, Bengaluru, Karnataka, India.
出版信息
J Contemp Dent Pract. 2015 May 1;16(5):389-93. doi: 10.5005/jp-journals-10024-1695.
BACKGROUND
Oral submucous fibrosis (OSF) and quid associated oral lichenoid lesions (QOLL) are caused because of areca nut chewing and both show very characteristic histological changes. The present study aims to determine the histopathological presence of lichenoid features in cases of OSF as well as to determine the presence of fibrosis in cases of QOLL.
MATERIALS AND METHODS
The study involved the retrospective analysis of hematoxylin and eosin stained slides of OSF (n = 50) and QOLL (n = 16).
RESULTS
Seven cases of OSF revealed histopathological features of lichenoid reaction and four cases of QOLL revealed the presence of fibrosis in the underlying connective tissue.
CONCLUSION
This study put forths a new finding that is, the presence of concomitant disease processes seen in the same patient at a histological level. It thus, stresses the need to evaluate all cases of OSF and QOLL for additional features which may be induced by areca nut chewing.
背景
口腔黏膜下纤维化（OSF）和咀嚼槟榔相关的口腔苔藓样病变（QOLL）均由咀嚼槟榔引起，且二者均呈现出非常典型的组织学变化。本研究旨在确定OSF病例中苔藓样特征的组织病理学表现，以及确定QOLL病例中纤维化的存在情况。
材料与方法
本研究对50例OSF和16例QOLL的苏木精-伊红染色切片进行回顾性分析。
结果
7例OSF显示出苔藓样反应的组织病理学特征，4例QOLL显示其下方结缔组织存在纤维化。
结论
本研究提出了一项新发现，即在组织学水平上，同一患者存在伴随的疾病过程。因此，强调了对所有OSF和QOLL病例评估可能由咀嚼槟榔诱发的其他特征的必要性。
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