Liver X receptors at the intersection of lipid metabolism and atherogenesis.
作者信息
Lee Stephen D, Tontonoz Peter
机构信息
Howard Hughes Medical Institute, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90095, USA.
Howard Hughes Medical Institute, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90095, USA.
出版信息
Atherosclerosis. 2015 Sep;242(1):29-36. doi: 10.1016/j.atherosclerosis.2015.06.042. Epub 2015 Jul 2.
Abstract
摘要
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Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion.溶血磷脂酰胆碱酰基转移酶3依赖性花生四烯酰磷脂的产生是甘油三酯分泌的关键决定因素。
Elife. 2015 Mar 25;4:e06557. doi: 10.7554/eLife.06557.
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Are there genetic paths common to obesity, cardiovascular disease outcomes, and cardiovascular risk factors?肥胖、心血管疾病结局和心血管危险因素是否存在共同的遗传途径？
Circ Res. 2015 Feb 27;116(5):909-22. doi: 10.1161/CIRCRESAHA.116.302888.
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Inflammation and immunity in diseases of the arterial tree: players and layers.动脉系统疾病中的炎症与免疫：参与者与层次
Circ Res. 2015 Jan 16;116(2):307-11. doi: 10.1161/CIRCRESAHA.116.301313.
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The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice.肝X受体-Idol轴对灵长类动物和小鼠的血浆低密度脂蛋白水平有不同的调节作用。
Cell Metab. 2014 Nov 4;20(5):910-918. doi: 10.1016/j.cmet.2014.10.001.
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Hepatic TRAP80 selectively regulates lipogenic activity of liver X receptor.肝脏TRAP80选择性调节肝脏X受体的脂肪生成活性。
J Clin Invest. 2015 Jan;125(1):183-93. doi: 10.1172/JCI73615. Epub 2014 Dec 1.
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Inactivating mutations in NPC1L1 and protection from coronary heart disease.NPC1L1基因的失活突变与冠心病防护
N Engl J Med. 2014 Nov 27;371(22):2072-82. doi: 10.1056/NEJMoa1405386. Epub 2014 Nov 12.
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Relative roles of ABCG5/ABCG8 in liver and intestine.ABCG5/ABCG8在肝脏和肠道中的相对作用。
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Cardiovascular risk and events in 17 low-, middle-, and high-income countries.17 个低收入、中收入和高收入国家的心血管风险和事件。
N Engl J Med. 2014 Aug 28;371(9):818-27. doi: 10.1056/NEJMoa1311890.
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Macrophage-independent regulation of reverse cholesterol transport by liver X receptors.肝脏X受体对胆固醇逆向转运的巨噬细胞非依赖性调节
Arterioscler Thromb Vasc Biol. 2014 Aug;34(8):1650-60. doi: 10.1161/ATVBAHA.114.303383. Epub 2014 Jun 19.
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