Ng S C, Lee M K, Teh A
Department of Pathology, Medical Faculty, University of Malaya, Kuala Lumpur.
Postgrad Med J. 1989 Nov;65(769):843-4. doi: 10.1136/pgmj.65.769.843.
A 72 year old man developed acute organic brain syndrome associated with marked eosinophilia following self medication with a variety of drugs. Investigations revealed no other known causes of eosinophilia. Withdrawal of drugs resulted in dramatic drop in eosinophil count paralleled by clinical resolution of neurological problems. To our knowledge drug-induced eosinophilia has not previously been associated with acute organic brain syndrome.
一名72岁男性在自行服用多种药物后出现急性器质性脑综合征,并伴有明显的嗜酸性粒细胞增多。检查未发现其他已知的嗜酸性粒细胞增多原因。停用药物后,嗜酸性粒细胞计数急剧下降,同时神经问题在临床上得到缓解。据我们所知,药物性嗜酸性粒细胞增多以前未曾与急性器质性脑综合征相关联。