市售植物源精油对口腔病原菌的抗菌活性。
Antibacterial activity of commercially available plant-derived essential oils against oral pathogenic bacteria.
作者信息
Bardají D K R, Reis E B, Medeiros T C T, Lucarini R, Crotti A E M, Martins C H G
机构信息
a Laboratório de Pesquisa em Microbiologia Aplicada , Universidade de Franca , Av. Dr. Armando Salles de Oliveira, 201 - Parque Universitário, CEP 14404-600, Franca , SP , Brazil.
b Departamento de Química , Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo , Ribeirão Preto , SP , Brazil.
出版信息
Nat Prod Res. 2016;30(10):1178-81. doi: 10.1080/14786419.2015.1043630. Epub 2015 Jul 13.
This work investigated the antibacterial activity of 15 commercially available plant-derived essential oils (EOs) against a panel of oral pathogens. The broth microdilution method afforded the minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) of the assayed EOs. The EO obtained from Cinnamomum zeylanicum (Lauraceae) (CZ-EO) displayed moderate activity against Fusobacterium nucleatum (MIC and MBC = 125 μg/mL), Actinomyces naeslundii (MIC and MBC = 125 μg/mL), Prevotella nigrescens (MIC and MBC = 125 μg/mL) and Streptococcus mutans (MIC = 200 μg/mL; MBC = 400 μg/mL). (Z)-isosafrole (85.3%) was the main chemical component of this oil. We did not detect cinnamaldehyde, previously described as the major constituent of CZ-EO, in specimens collected in other countries.
本研究调查了15种市售植物源精油（EOs）对一组口腔病原体的抗菌活性。采用肉汤微量稀释法测定了受试精油的最低抑菌浓度（MICs）和最低杀菌浓度（MBCs）。从锡兰肉桂（樟科）中提取的精油（CZ-EO）对具核梭杆菌（MIC和MBC = 125μg/mL）、内氏放线菌（MIC和MBC = 125μg/mL）、变黑普雷沃菌（MIC和MBC = 125μg/mL）和变形链球菌（MIC = 200μg/mL；MBC = 400μg/mL）表现出中等活性。（Z）-异黄樟素（85.3%）是该精油的主要化学成分。在其他国家收集的样本中，我们未检测到先前被描述为CZ-EO主要成分的肉桂醛。
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