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市售精油对变形链球菌的抗菌活性。

Antimicrobial activity of commercially available essential oils against Streptococcus mutans.

作者信息

Chaudhari Lalit Kumar D, Jawale Bhushan Arun, Sharma Sheeba, Sharma Hemant, Kumar C D Mounesh, Kulkarni Pooja Adwait

机构信息

Department of Oral Medicine and Radiology, ACPM Dental College, Dhule, Maharashtra, India.

出版信息

J Contemp Dent Pract. 2012 Jan 1;13(1):71-4. doi: 10.5005/jp-journals-10024-1098.

DOI:10.5005/jp-journals-10024-1098
PMID:22430697
Abstract

INTRODUCTION

Many essential oils have been advocated for use in complementary medicine for bacterial and fungal infections. However, few of the many claims of therapeutic efficacy have been validated adequately by either in vitro testing or in vivo clinical trials.

OBJECTIVE

To study the antibacterial activity of nine commercially available essential oils against Streptococcus mutans in vitro and to compare the antibacterial activity between each material.

METHODOLOGY

Nine pure essential oils; wintergreen oil, lime oil, cinnamon oil, spearmint oil, peppermint oil, lemongrass oil, cedarwood oil, clove oil and eucalyptus oil were selected for the study. Streptococcus mutans was inoculated at 37ºC and seeded on blood agar medium. Agar well diffusion assay was used to measure antibacterial activity. Zone of inhibition was measured around the filter paper in millimeters with vernier caliper.

RESULTS

Cinnamon oil showed highest activity against Streptococcus mutans followed by lemongrass oil and cedarwood oil. Wintergreen oil, lime oil, peppermint oil and spearmint oil showed no antibacterial activity.

CONCLUSION

Cinnamon oil, lemongrass oil, cedarwood oil, clove oil and eucalyptus oil exhibit antibacterial property against S. mutans.

CLINICAL SIGNIFICANCE

The use of these essential oils against S. mutans can be a viable alternative to other antibacterial agents as these are an effective module used in the control of both bacteria and yeasts responsible for oral infections.

摘要

引言

许多精油被提倡用于辅助治疗细菌和真菌感染。然而,众多关于治疗效果的说法中,很少有通过体外测试或体内临床试验得到充分验证的。

目的

研究九种市售精油对变形链球菌的体外抗菌活性,并比较每种材料之间的抗菌活性。

方法

选择九种纯精油;冬青油、酸橙油、肉桂油、留兰香油、薄荷油、柠檬草油、雪松木油、丁香油和桉叶油用于研究。将变形链球菌在37℃接种并接种在血琼脂培养基上。采用琼脂扩散法测定抗菌活性。用游标卡尺测量滤纸片周围的抑菌圈,以毫米为单位。

结果

肉桂油对变形链球菌的活性最高,其次是柠檬草油和雪松木油。冬青油、酸橙油、薄荷油和留兰香油没有抗菌活性。

结论

肉桂油、柠檬草油、雪松木油、丁香油和桉叶油对变形链球菌具有抗菌性能。

临床意义

使用这些精油对抗变形链球菌可以成为其他抗菌剂的可行替代品,因为它们是控制导致口腔感染的细菌和酵母菌的有效模块。

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