Wang Zhichong, Wu Jichun, Zhao Ningdong, Yang Yiyu, Chen Yegao
a Department of Medicinal Chemistry, School of Chemistry and Chemical Engineering, Yunnan Normal University , Chenggong New District, Kunming 650500 , China.
b Department of Natural Medicinal Chemistry, College of Pharmacy, Yanbian University , Yanji 133002 , China.
Nat Prod Res. 2016;30(2):241-5. doi: 10.1080/14786419.2015.1046131. Epub 2015 Jul 13.
Two new Lycopodium alkaloids, 4β-hydroxynankakurine B (1) and Δ(13,N),N(α)-methylphlegmarine-N(β)-oxide (2), together with three known analogues, lycoposerramine E (3), nankakurine B (4) and lobscurinol (5), were isolated from Phlegmariurus phlegmaria. Their structures were established by mass spectrometry and 1D and 2D NMR techniques.
从扁枝石松中分离出两种新的石松生物碱，4β-羟基南卡库林B（1）和Δ(13,N)，N(α)-甲基弗勒马里胺-N(β)-氧化物（2），以及三种已知类似物，石松色胺E（3）、南卡库林B（4）和洛布库林醇（5）。通过质谱分析以及一维和二维核磁共振技术确定了它们的结构。
