Running Alice
College of Nursing No. 211, Montana State University, Bozeman, MT 59717-3560, USA.
Evid Based Complement Alternat Med. 2015;2015:870640. doi: 10.1155/2015/870640. Epub 2015 Jun 11.
Breast cancer is one of the leading causes of cancer death among women of all races. Pain is a common symptom associated with cancer; 75-90% of cancer patients experience pain during their illness and up to 50% of that pain is undertreated. Unrelieved pain leads to increased levels of the stress hormone cortisol. The purpose of this study was to examine the impact of bioenergy on fecal cortisol levels for mice injected with murine mammary carcinoma 4T1 in two separate pilot studies. Using a multiple experimental group design, six to eight week old female BALB/c mice were injected with tumor and randomly assigned, in groups of 10, to daily treatment, every other day treatment, and no treatment groups. Five days after tumor cell injection, bioenergy interventions were begun for a period of ten consecutive days. Fecal samples were collected for each study and ELISA analysis was conducted at the end of both studies. For both studies, cortisol levels were decreased in the every other day treatment groups but remained high in the no treatment groups. Future studies utilizing bioenergy therapies on cortisol levels in a murine breast cancer model can begin to describe pain outcomes and therapeutic dose.
乳腺癌是所有种族女性癌症死亡的主要原因之一。疼痛是与癌症相关的常见症状;75%至90%的癌症患者在患病期间会经历疼痛,其中高达50%的疼痛未得到充分治疗。未缓解的疼痛会导致应激激素皮质醇水平升高。本研究的目的是在两项独立的初步研究中,研究生物能量对注射了鼠乳腺癌4T1的小鼠粪便皮质醇水平的影响。采用多实验组设计,将6至8周龄的雌性BALB/c小鼠注射肿瘤,并随机分成10只一组,分别给予每日治疗组、隔日治疗组和未治疗组。肿瘤细胞注射5天后,开始进行为期10天的生物能量干预。在每项研究中收集粪便样本,并在两项研究结束时进行ELISA分析。在两项研究中,隔日治疗组的皮质醇水平均下降,但未治疗组的皮质醇水平仍然很高。未来利用生物能量疗法对小鼠乳腺癌模型中皮质醇水平进行的研究可以开始描述疼痛结果和治疗剂量。