Auza N, Braun J P, Benard P, Thouvenot J P, Rico A G
Laboratoire Associe INRA Toxicologie Biochimique et Metabolique, Ecole Nationale Veterinaire, Toulouse, France.
Vet Hum Toxicol. 1989 Dec;31(6):535-7.
Two groups of 4 sheep received a daily iv injection of sodium heptamolybdate (100mg/day) or of saline for 2 weeks to study the hematological and plasma biochemical effects of molybdenum toxicosis. In molybdenum-dosed sheep, there was hypercupremia, mild anemia due to the decrease of copper concentration in the liver and moderate hepatocellular damage probably due to a direct toxic effect of molybdenum against the liver.
两组四只绵羊,一组每天静脉注射七钼酸钠(100毫克/天),另一组每天静脉注射生理盐水,持续两周,以研究钼中毒对血液学和血浆生化指标的影响。在注射钼的绵羊中,出现了高铜血症,因肝脏中铜浓度降低导致轻度贫血,以及可能由于钼对肝脏的直接毒性作用而引起的中度肝细胞损伤。