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绵羊实验性钼中毒时的血液学和血浆生化紊乱

Hematological and plasma biochemical disturbances in experimental molybdenum toxicosis in sheep.

作者信息

Auza N, Braun J P, Benard P, Thouvenot J P, Rico A G

机构信息

Laboratoire Associe INRA Toxicologie Biochimique et Metabolique, Ecole Nationale Veterinaire, Toulouse, France.

出版信息

Vet Hum Toxicol. 1989 Dec;31(6):535-7.

PMID:2617835
Abstract

Two groups of 4 sheep received a daily iv injection of sodium heptamolybdate (100mg/day) or of saline for 2 weeks to study the hematological and plasma biochemical effects of molybdenum toxicosis. In molybdenum-dosed sheep, there was hypercupremia, mild anemia due to the decrease of copper concentration in the liver and moderate hepatocellular damage probably due to a direct toxic effect of molybdenum against the liver.

摘要

两组四只绵羊,一组每天静脉注射七钼酸钠(100毫克/天),另一组每天静脉注射生理盐水,持续两周,以研究钼中毒对血液学和血浆生化指标的影响。在注射钼的绵羊中,出现了高铜血症,因肝脏中铜浓度降低导致轻度贫血,以及可能由于钼对肝脏的直接毒性作用而引起的中度肝细胞损伤。

相似文献

1
Hematological and plasma biochemical disturbances in experimental molybdenum toxicosis in sheep.绵羊实验性钼中毒时的血液学和血浆生化紊乱
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[The diagnostic significance of different blood parameters and liver biopsy in chronic copper poisoning of sheep].[不同血液参数及肝脏活检对绵羊慢性铜中毒的诊断意义]
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Effect of a high copper intake and different levels of molybdenum on the health of sheep.高铜摄入量和不同钼水平对绵羊健康的影响。
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Assessment of some clinical and laboratory variables for early diagnosis of cumulative copper poisoning in sheep.评估一些临床和实验室变量以早期诊断绵羊的累积性铜中毒。
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