Duan-Porter Wei, Coeytaux Remy R, McDuffie Jennifer R, Goode Adam P, Sharma Poonam, Mennella Hillary, Nagi Avishek, Williams John W
Dept of Health Services Research and Development, Durham VA Medical Center, Durham, NC.
J Phys Act Health. 2016 Mar;13(3):281-8. doi: 10.1123/jpah.2015-0027. Epub 2015 Jul 14.
This study describes evidence of yoga's effectiveness for depressive disorders, general anxiety disorder (GAD), panic disorder (PD), and posttraumatic stress disorder (PTSD) in adults. We also address adverse events associated with yoga.
We searched multiple electronic databases for systematic reviews (SRs) published between 2008 and July 2014, randomized controlled trials (RCTs) not identified in eligible SRs, and ongoing RCTs registered with ClincalTrials.gov.
We identified 1 SR on depression, 1 for adverse events, and 3 addressing multiple conditions. The high-quality depression SR included 12 RCTs (n = 619) that showed improved short-term depressive symptoms (standardized mean difference, -0.69, 95% confidence interval, -0.99 to -0.39), but there was substantial variability (I2 = 86%) and a high risk of bias for 9 studies. Three SRs addressing multiple conditions identified 4 nonrandomized studies (n = 174) for GAD/PD and 1 RCT (n = 8) and 2 nonrandomized studies (n = 22) for PTSD. We separately found 1 RCT (n = 13) for GAD and 2 RCTs (n = 102) for PTSD. Collectively, these studies were inconclusive for the effectiveness of yoga in treating GAD/PD and PTSD. The high-quality SR for adverse events included 37 primary reports (n = 76) in which inversion postures were most often implicated. We found 5 ongoing trials (3 for PTSD).
Yoga may improve short-term depressive symptoms, but evidence for GAD, PD, and PTSD remain inconclusive.
本研究描述了瑜伽对成人抑郁症、广泛性焦虑症（GAD）、恐慌症（PD）和创伤后应激障碍（PTSD）有效性的证据。我们还探讨了与瑜伽相关的不良事件。
我们在多个电子数据库中检索了2008年至2014年7月发表的系统评价（SR）、符合条件的SR中未纳入的随机对照试验（RCT）以及在ClinicalTrials.gov注册的正在进行的RCT。
我们确定了1篇关于抑郁症的SR、1篇关于不良事件的SR以及3篇涉及多种病症的SR。高质量的抑郁症SR纳入了12项RCT（n = 619），结果显示短期抑郁症状有所改善（标准化均值差为-0.69，95%置信区间为-0.99至-0.39），但存在较大异质性（I2 = 86%），9项研究存在较高偏倚风险。3篇涉及多种病症的SR确定了4项针对GAD/PD的非随机研究（n = 174）、1项针对PTSD的RCT（n = 8）以及2项针对PTSD的非随机研究（n = 22）。我们另外还发现了1项针对GAD的RCT（n = 13）和2项针对PTSD的RCT（n = 102）。总体而言，这些研究对于瑜伽治疗GAD/PD和PTSD的有效性尚无定论。关于不良事件的高质量SR纳入了37篇原始报告（n = 76），其中头倒立姿势最常涉及。我们发现有5项正在进行的试验（3项针对PTSD）。
瑜伽可能改善短期抑郁症状，但对于GAD、PD和PTSD的证据仍不确凿。
