早期营养对生长及免疫反应性生长调节素A循环水平的影响。

The influence of early nutrition on growth and the circulating levels of immunoreactive somatomedin A.

作者信息

Sara V R, Hall K, Gren B S, Finnson K, Wetterberg L

出版信息

J Dev Physiol. 1979 Oct;1(5):343-50.

Abstract

The effect of nutrition during early development on growth and serum immunoreactive somatomedin A was examined in rats by rearing in small or large liters. At weaning, body weight, brain weight, liver weight and DNA content was significantly reduced in rats whose nutrition was restricted by rearing in large litters. Brain DNA content was significantly altered. Serum somatomedin A was significantly reduced in the growth-retarded rats as compared to those whose growth was enhanced by rearing in small litters. Similarly, maternal serum somatomedin A was significantly reduced in rats nursing large litters.

摘要

通过将大鼠饲养在大小不同的窝中，研究早期发育期间营养对其生长和血清免疫反应性生长调节素A的影响。断奶时，饲养在大窝中导致营养受限的大鼠，其体重、脑重、肝重和DNA含量显著降低。脑DNA含量发生显著改变。与饲养在小窝中生长增强的大鼠相比，生长迟缓的大鼠血清生长调节素A显著降低。同样，哺乳大窝幼崽的大鼠母体血清生长调节素A也显著降低。

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