Department of Molecular Medicine, University of Padova, Viale G. Colombo 3, 35121, Padova, Italy.
Laboratory of Functional Foods, IMDEA-Food, CEI UAM + CSIC, Madrid, Spain.
Mol Neurobiol. 2016 Aug;53(6):4083-4093. doi: 10.1007/s12035-015-9349-1. Epub 2015 Jul 22.
Population aging is a worldwide demographic trend. Consequently, the prevalence of chronic age-related conditions such as clinically diagnosed neurological diseases, cognitive decline, and dementia will significantly increase in the near future. The important role of diets and healthy lifestyle as preventative of neurodegenerative diseases is widely accepted nowadays, and it may provide preventive strategies in very early, non-symptomatic phases of dementia well, especially because there are still no effective treatments for it. In this article, we review the known effects of selected micronutrients on the aging brain and we propose strategies for dietary improvements.
人口老龄化是一个全球性的人口趋势。因此,在不久的将来,临床上诊断的神经退行性疾病、认知能力下降和痴呆等慢性与年龄相关疾病的患病率将显著增加。如今,人们广泛接受饮食和健康生活方式在预防神经退行性疾病方面的重要作用,而且它可能在痴呆症的非常早期、无症状阶段提供有效的预防策略,特别是因为目前还没有有效的治疗方法。在本文中,我们回顾了选定的微量营养素对衰老大脑的已知影响,并提出了改善饮食的策略。