Oshima Megumi, Hamba Hidenori, Sadr Alireza, Nikaido Toru, Tagami Junji
Am J Dent. 2015 Jun;28(3):123-7.
To evaluate the effect of a fluoride-containing polymer-based desensitizer on prevention of root demineralization using micro-computed tomography (micro-CT).
Bovine root dentin blocks were divided into four groups; no treatment (Control); 1% oxalic acid (OA); MS Coat One containing methacrylate-co-p-styrene sulfonic acid (MS polymer) and 1% oxalic acid (MSO); and MS Coat F containing MS polymer, 1% oxalic acid and 3,000 ppm sodium fluoride (MSF). A window of the dentin surface was treated with each solution. The blocks were scanned using micro-CT after demineralization (pH 4.5, 5 hours). The dentin surfaces before and after demineralization were examined by scanning electron microscopy (SEM). Fluoride ion release was measured using a fluoride ion-specific electrode. The data were statistically analyzed using one-way ANOVA and Tukey's test (α = 0.05).
MSF showed the lowest mineral loss (3176.5 ± 630.5 vol%μm), which was significantly different from Control (4600.1 ± 1053.4 vol%μm), OA (3992.7 ± 899.0 vol%μm) and MSO (3900.2 ± 645.4 vol%μm). [corrected]. Under the SEM observations, the dentin tubules appeared to be blocked after all desensitizer treatments. After demineralization, the exposure of dentin tubules was clearer in OA and MSO compared to MSF which showed sealed dentin tubules after demineralization. Fluoride ion release was detected only in the MSF group.
使用显微计算机断层扫描（micro-CT）评估含氟聚合物脱敏剂对预防牙根脱矿的效果。
将牛牙根牙本质块分为四组；未处理（对照组）；1%草酸（OA）；含甲基丙烯酸-co-p-苯乙烯磺酸的MS Coat One（MS聚合物）和1%草酸（MSO）；以及含MS聚合物、1%草酸和3000 ppm氟化钠的MS Coat F（MSF）。用每种溶液处理牙本质表面的一个窗口。脱矿（pH 4.5，5小时）后使用micro-CT扫描这些块体。通过扫描电子显微镜（SEM）检查脱矿前后的牙本质表面。使用氟离子特异性电极测量氟离子释放。数据采用单因素方差分析和Tukey检验进行统计学分析（α = 0.05）。
MSF显示出最低的矿物质损失（3176.5 ± 630.5 vol%μm），与对照组（4600.1 ± 1053.4 vol%μm）、OA组（3992.7 ± 899.0 vol%μm）和MSO组（3900.2 ± 645.4 vol%μm）有显著差异。[校正后]。在SEM观察下，所有脱敏剂处理后牙本质小管似乎被堵塞。脱矿后，与脱矿后显示封闭牙本质小管的MSF相比，OA和MSO组的牙本质小管暴露更清晰。仅在MSF组检测到氟离子释放。
